. . MR scan of brain (1.5 Tesla), patient aged 30 years. (A) Axial T2-weighted sequences at midbrain level show disproportionate volume loss and signal.

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Presentation transcript:

. . MR scan of brain (1.5 Tesla), patient aged 30 years. (A) Axial T2-weighted sequences at midbrain level show disproportionate volume loss and signal hyperintensity surrounding the red nucleus and substantia nigra, simulating the ‘giant panda’ sign (arrow). (B) Axial T2-weighted sequences at corpus striatum level show hypointensity of the globi pallidi and the putamen shows volume loss and a hyperintense rim (arrows). (C) Axial T2*-weighted gradient-echo sequence confirms mineralisation of the globi pallidi (arrows). (D and E) Coronal FLAIR sequences through the dentate nuclei and midbrain show hyperintense signal change within the cerebellar white matter and surrounding the mineralised dentate nuclei (arrows in panel D) and midbrain (arrow in panel E). Michael H Parkinson et al. Pract Neurol 2014;14:409-414 ©2014 by BMJ Publishing Group Ltd