Prospective randomized neurocognitive and S-100 study of hypothermic circulatory arrest, retrograde brain perfusion, and antegrade brain perfusion for.

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Presentation transcript:

Prospective randomized neurocognitive and S-100 study of hypothermic circulatory arrest, retrograde brain perfusion, and antegrade brain perfusion for aortic arch operations Lars G Svensson, MD, PhD, Edward M Nadolny, Dana L Penney, PhD, Jerilynn Jacobson, MA, Wendy A Kimmel, Michael H Entrup, MD, Richard S D’Agostino, MD The Annals of Thoracic Surgery Volume 71, Issue 6, Pages 1905-1912 (June 2001) DOI: 10.1016/S0003-4975(01)02570-X

Fig 1 S-100 levels in the individual hypothermic arrest groups. (ANTE = antegrade brain perfusion; CPB = cardiopulmonary bypass; DHCA = deep hypothermic circulatory arrest; ENDCA = end of circulatory arrest; ENDCPB = end of cardiopulmonary bypass; ENDCOOL = end of cooling; ENDWARM = end of warming; H = hours postoperatively; OR = leaving operating room; RBP = retrograde brain perfusion; open diamond = deep hypothermic circulatory arrest; open square = retrograde brain perfusion; closed triangle = antegrade brain transfusion.) The Annals of Thoracic Surgery 2001 71, 1905-1912DOI: (10.1016/S0003-4975(01)02570-X)

Fig 2 S-100 levels during the course of the operation comparing coronary artery bypass patients with hypothermic arrest. (CA = circulatory arrest; CAB = coronary artery bypass; CPB = cardiopulmonary bypass; ENDCA/PPREW = end of circulatory arrest or prewarming; ENDCOOL = end of cooling; ENDCPB = end of cardiopulmonary bypass; ENDWARM = end of warming; H = hours postoperatively; OR = before leaving operating room; closed diamond = circulatory arrest; open square = coronary artery bypass.) The Annals of Thoracic Surgery 2001 71, 1905-1912DOI: (10.1016/S0003-4975(01)02570-X)