A 44-year-old woman with a history of anxiety disorder presenting with acute right facial weakness and expressive aphasia. A 44-year-old woman with a history of anxiety disorder presenting with acute right facial weakness and expressive aphasia. She had no known history of prior stroke. CTP demonstrates a focal area of hypoperfusion in the left frontal lobe within an area of chronic-appearing infarct (arrows). Chronic infarcts have measurable though diminished perfusion. Areas of acute infarct adjacent to chronic infarcts may, therefore, be difficult to detect. NCCT (A), CBF (B), CBV (C), at presentation; DWI (D) 1 day later. Y.W. Lui et al. AJNR Am J Neuroradiol 2010;31:1552-1563 ©2010 by American Society of Neuroradiology