Associations of hemodialysis dose and session length with mortality risk in Australian and New Zealand patients M.R. Marshall, B.G. Byrne, P.G. Kerr,

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Associations of hemodialysis dose and session length with mortality risk in Australian and New Zealand patients M.R. Marshall, B.G. Byrne, P.G. Kerr, S.P. McDonald Kidney International Volume 69, Issue 7, Pages 1229-1236 (April 2006) DOI: 10.1038/sj.ki.5000188 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Distribution of HD session length and dose within the study cohort. Kidney International 2006 69, 1229-1236DOI: (10.1038/sj.ki.5000188) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 2 Distribution of HD session length by categories of Kt/V. Kidney International 2006 69, 1229-1236DOI: (10.1038/sj.ki.5000188) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 3 Hazard ratios for mortality within study cohort according to selected predictive variables. Hazard ratios were derived within a multivariate Cox proportional-hazard model, with shared frailty for each treatment centre. Asterisks indicate the reference categories. Horizontal bars indicate 95% confidence intervals. Kidney International 2006 69, 1229-1236DOI: (10.1038/sj.ki.5000188) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 4 Univariate and multivariate fractional polynomial graphs depicting the relationship between both HD session length and dose with mortality risk. The multivariate graphs are fully adjusted for patient demographic and co-morbid medical conditions, and HD session length and dose in the other's respective analyses. Shaded areas indicate 95% confidence intervals. Kidney International 2006 69, 1229-1236DOI: (10.1038/sj.ki.5000188) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 5 Hazard ratios (HR) for mortality by HD session length and body mass index (BMI). The multivariate analyses are fully adjusted using the final regression model. All HR are relative to the group with BMI 25–29 and session length 4.5–4.9 h. Mortality risk is the same for different session lengths in group with BMI <25 (P=0.85), although differences are more likely in the groups with BMI 25–29 (P=0.01) and ≥30 (P=0.06). Error bars indicate 95% confidence intervals. Kidney International 2006 69, 1229-1236DOI: (10.1038/sj.ki.5000188) Copyright © 2006 International Society of Nephrology Terms and Conditions