(A–D) Gradient echo T2*-weighted axial MRI of the brain shows a rim of hypointensity (consistent with the presence of haemosiderin deposits in the leptomeninges.

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The if I Only Had a Brain… Will Kleinelp Associate professor Department of Biology.
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(A–D) Gradient echo T2*-weighted axial MRI of the brain shows a rim of hypointensity (consistent with the presence of haemosiderin deposits in the leptomeninges and subpial tissue) on the surface of cerebellum, brain stem, and inferior part of cerebral hemispheres (sylvian and interhemispheric fissures, and basal cisterns). (A–D) Gradient echo T2*-weighted axial MRI of the brain shows a rim of hypointensity (consistent with the presence of haemosiderin deposits in the leptomeninges and subpial tissue) on the surface of cerebellum, brain stem, and inferior part of cerebral hemispheres (sylvian and interhemispheric fissures, and basal cisterns). Please note the particular involvement of superior cerebellar folia (B, C) and the hypointensity on eighth (A) and, less conspicuously, fifth (B) cranial nerves bilaterally. (E–G) MRI of the spine. (E) T2 weighted sagittal image shows a hypointense rim surrounding the spinal cord. (F) T2 weighted coronal image at lumbar level demonstrates intradural extramedullary expanding lesions at L2–L3 and L4 levels, respectively, giving inhomogeneous signal due to intrinsic iso-hyperintensity and concomitant hypointensities consistent with haemosiderin. (G) On T1 weighted midsagittal image after intravenous gadolinium DTPA, the expanding lesion at L2–L3 level appears markedly enhanced, as did the minor lateral lesion at L4 level. This feature, as well as the presence of intrinsic haemosiderin, is consistent with the high vascularity of myxopapillary ependymomas, a subtype of glioma occurring almost exclusively in the filum terminale and conus medullaris, and accounting for nearly 90% of primary tumours in the cauda equina region. A Messori et al. J Neurol Neurosurg Psychiatry 2004;75:188-190 ©2004 by BMJ Publishing Group Ltd