Use of Utrogestan during controlled ovarian hyperstimulation in normally ovulating women undergoing in vitro fertilization or intracytoplasmic sperm injection.

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Presentation transcript:

Use of Utrogestan during controlled ovarian hyperstimulation in normally ovulating women undergoing in vitro fertilization or intracytoplasmic sperm injection treatments in combination with a “freeze all” strategy: a randomized controlled dose-finding study of 100 mg versus 200 mg Xiuxian Zhu, M.D., Hongjuan Ye, M.D., Yonglun Fu, M.D., Ph.D. Fertility and Sterility Volume 107, Issue 2, Pages 379-386.e4 (February 2017) DOI: 10.1016/j.fertnstert.2016.10.030 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Serum hormone profiles present during ovarian stimulation in the two regimens. The green lines represent the low-dose group (100 mg/d Utrogestan) and the red lines the high-dose group (200 mg/d Utrogestan). *P<.05 at the time point. MC = menstrual cycle day. Fertility and Sterility 2017 107, 379-386.e4DOI: (10.1016/j.fertnstert.2016.10.030) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Flowchart of the study. FET = frozen-thawed embryo transfer. Fertility and Sterility 2017 107, 379-386.e4DOI: (10.1016/j.fertnstert.2016.10.030) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 The number of patients with profound LH suppression (LH <1.2 IU). The red columns represent the low-dose group (100 mg/d Utrogestan) and the blue column the high-dose group (200 mg/d Utrogestan). *P<.05. Fertility and Sterility 2017 107, 379-386.e4DOI: (10.1016/j.fertnstert.2016.10.030) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions