Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma Julianna K. Bronk, Nandita Guha-Thakurta,

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Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma Julianna K. Bronk, Nandita Guha-Thakurta, Pamela K. Allen, Anita Mahajan, David R. Grosshans, Susan L. McGovern Clinical and Translational Radiation Oncology Volume 9, Pages 30-34 (February 2018) DOI: 10.1016/j.ctro.2018.01.002 Copyright © 2018 The Authors Terms and Conditions

Fig. 1 A 41 year old man with a grade II astrocytoma in the right temporal lobe treated with proton therapy to 54 GyRBE, 3.5 months after subtotal resection. (A) Post-contrast axial T1 weighted image demonstrates a right temporal lobe resection cavity with linear enhancement along the posterior margin. (B) One month after radiation, imaging reveals nodular enhancement along the medial aspect of the resection margin. (C) The enhancement resolved without any additional therapy on follow-up MRI one year after proton therapy. Clinical and Translational Radiation Oncology 2018 9, 30-34DOI: (10.1016/j.ctro.2018.01.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 (A) PFS for patients with PsP vs. patients without PsP. PFS at 3 years was 100% in patients with PsP and 61.6% in patients without PsP (p = .03). (B) OS for patients with PsP vs. patients without PsP. OS at 3 years was 100% in patients with PsP and 82.6% in patients without PsP (p = .04). Clinical and Translational Radiation Oncology 2018 9, 30-34DOI: (10.1016/j.ctro.2018.01.002) Copyright © 2018 The Authors Terms and Conditions