Begum Akay, MD, Junewai L. Reoma, MD, Daniele Camboni, MD, Joshua R

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Presentation transcript:

In-Parallel Artificial Lung Attachment at High Flows in Normal and Pulmonary Hypertension Models Begum Akay, MD, Junewai L. Reoma, MD, Daniele Camboni, MD, Joshua R. Pohlmann, MS, John M. Albert, BS, Ayushi Kawatra, BS, Ayanna D. Gouch, BS, Robert H. Bartlett, MD, Keith E. Cook, PhD The Annals of Thoracic Surgery Volume 90, Issue 1, Pages 259-265 (July 2010) DOI: 10.1016/j.athoracsur.2010.03.085 Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 The MC3 Biolung (compliance chamber not shown). The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Artificial lung attachment and instrumentation. (PAP = pulmonary artery pressure.) The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Cardiac output versus the percentage of cardiac output shunted to the artificial lung at all three dobutamine doses in normal sheep. (BL = baseline.) The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Cardiac output versus the percentage of cardiac output shunted to the artificial lung at all three dobutamine doses in sheep with chronic pulmonary hypertension. (BL = baseline.) The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Pulmonary system zeroth harmonic impedance modulus, Z0, versus the percentage of cardiac output diverted to the artificial lung in normal sheep. (BL = baseline.) The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Pulmonary system zeroth harmonic impedance modulus, Z0, versus the percentage of cardiac output diverted to the artificial lung in sheep with chronic pulmonary hypertension. (BL = baseline.) The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Biolung resistance as a function of flow rate. The Annals of Thoracic Surgery 2010 90, 259-265DOI: (10.1016/j.athoracsur.2010.03.085) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions