Mean change from baseline in 6MWD in (A) Chinese patients with PAH in PATENT-1 and (B) Chinese patients with CTEPH in CHEST-1. Mean change from baseline.

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Mean change from baseline in 6MWD in (A) Chinese patients with PAH in PATENT-1 and (B) Chinese patients with CTEPH in CHEST-1. Mean change from baseline in 6MWD in (A) Chinese patients with PAH in PATENT-1 and (B) Chinese patients with CTEPH in CHEST-1. Mean (±SEM) changes from baseline in 6MWD are shown for the modified intention-to-treat Chinese population without imputation of missing values, with the imputed values also provided at week 12 (PATENT-1) and week 16 (CHEST-1). The number of patients at each time point is indicated below the graph. Missing data were imputed at week 12/16 according to the last observation carried forward, except in cases of death or clinical worsening without a termination visit, where the worst value (0 m) was imputed. 6MWD, 6 min walking distance; CTEPH, chronic thromboembolic pulmonary hypertension; PAH, pulmonary arterial hypertension. Chen Wang et al. Heart Asia 2016;8:74-82 Copyright © Asia Pacific Heart Association, British Cardiovascular Society & BMJ Publishing Group Ltd. All rights reserved.