Volume 57, Issue 2, Pages (October 2000)

Slides:

Advertisements

Similar presentations

Renal involvement in hepatitis C infection: Cryoglobulinemic glomerulonephritis Giuseppe D’Amico Kidney International Volume 54, Issue 2, Pages

Advertisements

Volume 62, Issue 6, Pages (December 2002)

Volume 61, Issue 4, Pages (April 2002)

Effect of oleuropein against chemotherapy drug-induced histological changes, oxidative stress, and DNA damages in rat kidney injury Fatime Geyikoglu,

E. Homsi, P. Janino, J.B.L. de Faria Kidney International

Volume 66, Issue 1, Pages (July 2004)

Volume 66, Issue 6, Pages (December 2004)

Volume 60, Issue 6, Pages (December 2001)

Volume 80, Issue 8, Pages (October 2011)

The Case ∣ Acute renal failure and anemia

Volume 55, Issue 4, Pages (April 1999)

Volume 61, Issue 2, (February 2002)

Volume 58, Issue 2, Pages (August 2000)

Volume 66, Issue 6, Pages (December 2004)

Volume 54, Issue 2, Pages (August 1998)

Volume 54, Issue 5, Pages (November 1998)

Volume 64, Issue 1, Pages (July 2003)

Vitamin E attenuates crystal formation in rat kidneys: Roles of renal tubular cell death and crystallization inhibitors H.-S. Huang, J. Chen, C.-F. Chen,

Volume 68, Issue 3, Pages (September 2005)

Volume 60, Issue 1, Pages (July 2001)

Vikas Chander, PhD, Kanwaljit Chopra, PhD Journal of Vascular Surgery

Volume 71, Issue 8, Pages (April 2007)

Volume 84, Issue 2, Pages (August 2013)

Volume 54, Issue 3, Pages (September 1998)

Volume 82, Issue 8, Pages (October 2012)

Volume 60, Issue 5, Pages (November 2001)

Comorbidity and confounding in end-stage renal disease

Volume 70, Issue 11, Pages (December 2006)

Volume 61, Issue 3, Pages (March 2002)

Volume 56, Issue 4, Pages (October 1999)

Volume 54, Issue 3, Pages (September 1998)

Volume 73, Issue 12, Pages (June 2008)

Volume 80, Issue 8, Pages (October 2011)

Resistance to ischemic acute renal failure in the Brown Norway rat: A new model to study cytoprotection David P. Basile, Deborah Donohoe, X.I.A. Cao,

Volume 56, Issue 2, Pages (August 1999)

Volume 63, Issue 5, Pages (May 2003)

Volume 70, Issue 7, Pages (October 2006)

Volume 61, Issue 4, Pages (April 2002)

Volume 66, Issue 1, Pages (July 2004)

Functional sodium magnetic resonance imaging of the intact rat kidney

Volume 54, Issue 4, Pages (October 1998)

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Volume 57, Issue 6, Pages (June 2000)

Volume 64, Pages S21-S26 (October 2003)

Volume 73, Issue 3, Pages (February 2008)

Volume 60, Issue 6, Pages (December 2001)

Volume 56, Issue 4, Pages (October 1999)

Volume 54, Issue 1, Pages (July 1998)

Contribution of tubular injury to loss of remnant kidney function

Recapitulation of phylogeny by ontogeny in nephrology

H+-ATPase activity on unilateral ureteral obstruction: Interaction of endogenous nitric oxide and angiotensin II Patricia G. Valles, Walter A. Manucha

Volume 76, Issue 1, Pages 6-7 (July 2009)

Volume 80, Issue 7, Pages (October 2011)

Volume 64, Issue 3, Pages (September 2003)

Volume 63, Issue 1, Pages (January 2003)

Organ transplantation goes to the movies

Volume 62, Issue 4, Pages (October 2002)

David Z. Levine, M.D., Michelle Iacovitti, Kevin D. Burns, Amy Slater

Volume 58, Issue 4, Pages (October 2000)

Inflammatory cells in ischemic acute renal failure

Effect of ischemia on localization of heat shock protein 25 in kidney

Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failure D.W. Johnson, B. Pat, D.A. Vesey, Z.

Volume 72, Issue 4, Pages (August 2007)

David A. Ferenbach, David C. Kluth, Jeremy Hughes Kidney International

Volume 70, Issue 3, Pages (August 2006)

J.S. Schlondorff, G.P. Mendez, H.G. Rennke, C.C. Magee

E. Homsi, P. Janino, J.B.L. de Faria Kidney International

The tubulointerstitium in progressive diabetic kidney disease: More than an aftermath of glomerular injury? Richard E. Gilbert, Mark E. Cooper Kidney.

Glomerular monocytes predict worse outcomes after acute renal allograft rejection independent of C4d status Kathryn J. Tinckam, Ognjenka Djurdjev, Alex.

Presentation transcript:

Volume 57, Issue 2, Pages 526-533 (October 2000) Contribution of γ glutamyl transpeptidase to oxidative damage of ischemic rat kidney Juan C. Cutrín, M.D., Ph.D., Barbara Zingaro, Simonetta Camandola, Alberto Boveris, Alfonso Pompella, Giuseppe Poli Kidney International Volume 57, Issue 2, Pages 526-533 (October 2000) DOI: 10.1046/j.1523-1755.2000.00871.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Effects of 25 minutes of ischemia on the γ glutamyl transpeptidase (GGT) activity of rat kidney. (A) Cortex. (B) Outer medulla. Values are means ± SE from five rats per experimental group. aDifferent from control (P < 0.05); bdifferent from ischemia (P < 0.01); cdifferent from control (P < 0.05). Kidney International 2000 57, 526-533DOI: (10.1046/j.1523-1755.2000.00871.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Histochemistry of GGT activity in kidneys from control and acivicin-pretreated rats. (a) Renal inner cortex of a control rat. (b) Renal inner cortex of a rat pretreated with acivicin. G, glomeruli; arrows, proximal tubules. Kidney International 2000 57, 526-533DOI: (10.1046/j.1523-1755.2000.00871.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 3 Histochemistry of GGT activity in the inner cortex of ischemic rat kidneys in the presence or absence of acivicin pretreatment. (a) Inner cortex of ischemic kidney from acivicin-untreated animal. (b) Inner cortex of ischemic kidney from acivicin-treated rat. Arrows, proximal tubules; arrowheads, desquamated tubular cells; asterisks, dilated proximal tubules. Kidney International 2000 57, 526-533DOI: (10.1046/j.1523-1755.2000.00871.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 4 Histochemistry of GGT activity in the outer medulla of ischemic rat kidneys in the presence or absence of acivicin treatment. (a) Outer medulla of ischemic kidney from control rat. (b) Outer medulla of ischemic kidney from acivicin-treated rat. Arrows, proximal tubules; arrowheads, desquamated tubular cells; asterisks, dilated proximal tubules. Kidney International 2000 57, 526-533DOI: (10.1046/j.1523-1755.2000.00871.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 5 Effect of 25 minutes of ischemia on malondialdehyde (MDA) levels in rat kidney. (A) Cortex. (B) Medulla. Values are means ± SE from five animals per experimental group. aDifferent from control (P < 0.05); bdifferent from ischemia + acivicin (P < 0.001). Kidney International 2000 57, 526-533DOI: (10.1046/j.1523-1755.2000.00871.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 6 Effect of 25 minutes of ischemia on GSH content of rat kidney. (A) Cortex. (B) Medulla. Values are means ± SE from five animals per experimental group. aDifferent from control (P < 0.001); bdifferent from control (P < 0.01); cdifferent from ischemia (P < 0.03). Kidney International 2000 57, 526-533DOI: (10.1046/j.1523-1755.2000.00871.x) Copyright © 2000 International Society of Nephrology Terms and Conditions