Arrhythmogenic triggers associated with an autonomic response from a posteroseptal region after extensive ablation in a patient with long-standing atrial.

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Date of download: 7/6/2016 Copyright © The American College of Cardiology. All rights reserved. From: Catheter-induced linear lesions in theleft atrium.

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Arrhythmogenic triggers associated with an autonomic response from a posteroseptal region after extensive ablation in a patient with long-standing atrial fibrillation Naoto Kino, MD, Toshiya Kurotobi, MD, PhD, Kazato Ito, MD, Daisuke Tonomura, MD, Kentaro Yano, MD, Yoshihisa Shimada, MD, PhD HeartRhythm Case Reports Volume 1, Issue 2, Pages 68-72 (March 2015) DOI: 10.1016/j.hrcr.2015.01.011 Copyright © 2015 Heart Rhythm Society Terms and Conditions

Figure 1 Contrast medium was injected from a long sheath located at the CS ostium into the AP projection. CS angiography revealed a dilated CS ostium with a diverticulum (arrow) (A). Adjustable 20-pole catheters are located in the LAA and the SVC ostium, and the ablation catheter is located at the upper margin of the CS ostium (B). After a contrast injection, the AF temporarily terminated, but a new AF episode immediately occurred. The earliest activated site was consistent with the CS ostium. Although multipolar catheters were widely spaced in both atria, the sequence of the earliest activation seems to be lined vertically, implying a focus originating from the septal region. The R-R interval during SR just before the AF initiation was 932 ms, implying that there was parasympathetic coactivation during the isoproterenol infusion (C). ABL = ablation; AF = atrial fibrillation; AP = anteroposterior; CS = coronary sinus; dis = distal electrode; LAA = left atrial appendage; prox = proximal electrode; SR = sinus rhythm; SVC = superior vena cava. HeartRhythm Case Reports 2015 1, 68-72DOI: (10.1016/j.hrcr.2015.01.011) Copyright © 2015 Heart Rhythm Society Terms and Conditions

Figure 2 A remarkable bradycardic response during HFS (20 Hz, 30 mA, pulse width 10 ms) was also observed in that area. The mean heart rate was 100 beats/min, and the blood pressure was approximately 80 mm Hg just before the HFS (A). RF energy applications of up to 35 W successfully terminated the AF at the base of the aneurysm and the CS ostium. The AF cycle length just before the AF termination recorded in the LAA was 174–191 ms. Disorganized complex local electrograms were observed only around the CS ostium (B). ABL = ablation; AF = atrial fibrillation; CS = coronary sinus; BP = blood pressure; ECG = electrocardiogram; GP = ganglionated plexus; HFS = high-frequency stimulation; LAA = left atrial appendage; RF = radiofrequency; SVC = superior vena cava. HeartRhythm Case Reports 2015 1, 68-72DOI: (10.1016/j.hrcr.2015.01.011) Copyright © 2015 Heart Rhythm Society Terms and Conditions

Figure 3 Voltage map using the NavX EnSite Velocity system (St Jude Medical, Inc, St. Paul, MN). The left panel is an AP view, and the right panel is a PA view. The voltage map shows a low-voltage scar zone detected around the PVs and left lateral area (gray, <0.2 mV; purple, >1.5 mV). The green dots represent the ablation sites (red dots, AF termination sites during an RF energy application possibly consistent with the CS ostium and the neck of the diverticulum). Multiple RF energy applications gradually decreased the incidence of any spontaneous AF occurrences, and then the AF could finally no longer be induced. AF = atrial fibrillation; AP = anteroposterior; CS = coronary sinus; PA = posteroanterior; PV = pulmonary vein; RF = radiofrequency. HeartRhythm Case Reports 2015 1, 68-72DOI: (10.1016/j.hrcr.2015.01.011) Copyright © 2015 Heart Rhythm Society Terms and Conditions