Volume 56, Issue 5, Pages (November 1999)

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Presentation transcript:

Volume 56, Issue 5, Pages 1912-1919 (November 1999) Renal allograft survival following acute rejection correlates with blood pressure levels and histopathology  Fernando G. Cosio, M.D., Ronald P. Pelletier, Daniel D. Sedmak, Todd E. Pesavento, Mitchell L. Henry, Ronald M. Ferguson  Kidney International  Volume 56, Issue 5, Pages 1912-1919 (November 1999) DOI: 10.1046/j.1523-1755.1999.00752.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Kaplan–Meier plots of death censored graft survival in patients without acute rejection (AR; - - -), patients with one (—) and patients with two AR episodes (—; P < 0.0001 by Cox regression, indicating a significant difference between graft survival between both groups of patients with AR and patients without AR). Kidney International 1999 56, 1912-1919DOI: (10.1046/j.1523-1755.1999.00752.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Graft survival (%, y-axis) in patients with acute rejection (AR) and a post-AR serum creatinine concentration ≤2 mg/dl. The X-axis displays the average systolic blood pressure (BP) following AR (P = 0.0009, logistic regression). Kidney International 1999 56, 1912-1919DOI: (10.1046/j.1523-1755.1999.00752.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 3 Kaplan–Meier plots of death censored long-term graft survival in patients without acute rejection (AR; —), patients with AR and average post-AR systolic BP: <130 mm Hg (○—○), 130 to 140 mm Hg (□—□), 140 to 150 mm Hg (•—•), and> 150 mm Hg (▪—▪). Kidney International 1999 56, 1912-1919DOI: (10.1046/j.1523-1755.1999.00752.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 4 Graft survival (y-axis) in patients classified according to the histopathology of acute rejection (AR grade, x-axis). Note that graft survival in this analysis includes grafts lost any time post-transplant. Kidney International 1999 56, 1912-1919DOI: (10.1046/j.1523-1755.1999.00752.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 5 Kaplan–Meier plots of death censored graft survival in patients without AR (- - -), nonvascular AR (—), or vascular AR (—; P < 0.0001 by Cox analysis). Note that graft survival in this analysis includes grafts lost any time post-transplant. Kidney International 1999 56, 1912-1919DOI: (10.1046/j.1523-1755.1999.00752.x) Copyright © 1999 International Society of Nephrology Terms and Conditions