Centromeres Current Biology Lisa E. Kursel, Harmit S. Malik  Current Biology  Volume 26, Issue 12, Pages R487-R490 (June 2016) DOI: 10.1016/j.cub.2016.05.031 Copyright © 2016 Elsevier Ltd Terms and Conditions

Figure 1 A diversity of centromeres. Centromeres from a selection of eukaryotic organisms are represented by a series of immunofluorescence images showing DNA (DAPI, blue) and centromeres marked by centromeric proteins (green or red) unless otherwise specified. (A) Clustered point centromeres in anaphase from budding yeast Saccharomyces cerevisiae (image: Erica Hildebrand, Sue Biggins lab). Clustered regional centromeres in late anaphase from two fungi: (B) Candida albicans (image: Neha Varshney, Kaustuv Sanyal lab) and (C) Schizosaccharomyces pombe (image: Sharon White, Robin Allshire lab). (D) Regional centromeres of Homo sapiens metacentric chromosomes (centromeres at the center of the chromosome) during anaphase (image: Geert Kops lab). (E) Regional centromeres of Mus musculus acrocentric chromosomes (centromeres towards one end of the chromosome) during metaphase (centromeric minor satellite DNA repeats shown in red; image: Aiko Otsubo, Michael Lampson lab). (F) Regional centromeres in Drosophila melanogaster S2 cells during late anaphase (image: Leah Rosin, Barbara Mellone lab). (G) Holocentric chromosomes of the nematode Caenorhabditis elegans in early anaphase (left panel) and late anaphase (right panel) of a one-cell embryo (image: Bram Prevo, Arshad Desai lab). (H) Regional, metacentric chromosomes of Arabidopsis thaliana during anaphase (image: Mohan Marimuthu, Luca Comai/Simon Chan lab). (I) ‘Poly-metacentric’ metaphase chromosomes of the plant Pisum sativus (image: Pavel Neumann). (J) Holocentric chromosomes of the plant Rhynchospora pubera during pre-metaphase (left panel, ‘railroad tracks’), metaphase (middle panel) and anaphase (right panel) (image: Andreas Houben lab). (K) Regional centromere-containing chromosomes of the kinetoplastid Trypanosoma brucei cell during anaphase (DNA, pink; image: Bungo Akiyoshi lab). Current Biology 2016 26, R487-R490DOI: (10.1016/j.cub.2016.05.031) Copyright © 2016 Elsevier Ltd Terms and Conditions