Computational genomics

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Computational genomics Eugene V Koonin  Current Biology  Volume 11, Issue 5, Pages R155-R158 (March 2001) DOI: 10.1016/S0960-9822(01)00081-1

Fig. 1 A plot of the predicted number of protein-coding genes versus genome size. Mgen, Mycoplasma genitalium; Mjan, Methnococcus jannaschii (an archaeon); Ecoli, Escherichia coli; Scer, Saccharomyces cerevisiae (yeast); Cele, Caenorhabditis elegans (nematode); Atha, Arabidopsis thaliana (thale cress); Dmel, Drosophila melanogaster (fruit fly); Hsap, Homo sapiens. Current Biology 2001 11, R155-R158DOI: (10.1016/S0960-9822(01)00081-1)

Fig. 2 A simplified scheme for comparative analysis of predicted proteomes. (a) Library of domain-specific profiles used for protein domain recognition; (b) database of orthologous protein families; (c) comparison of domain architectures of orthologous proteins from the analyzed genomes revealing domain accretion and rearrangements; (d) comparison of domain counts in the analyzed genomes revealing lineage-specific expansions. Current Biology 2001 11, R155-R158DOI: (10.1016/S0960-9822(01)00081-1)