Racial differences in biochemical knee cartilage composition between African-American and Caucasian-American women with 3 T MR-based T2 relaxation time.

Slides:

Advertisements

Similar presentations

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.

Advertisements

The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement.

Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study

MR T1ρ and T2 of meniscus after acute anterior cruciate ligament injuries Amy Wang, Valentina Pedoia, Favian Su, Elijah Abramson, Martin Kretzschmar,

Subregional laminar cartilage MR spin–spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss – data from.

Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative M. Hakky, M. Jarraya,

T1ρ relaxation time of the meniscus and its relationship with T1ρ of adjacent cartilage in knees with acute ACL injuries at 3T R.I. Bolbos, Ph.D., T.M.

Functional cartilage MRI T2 mapping: evaluating the effect of age and training on knee cartilage response to running T.J. Mosher, Y. Liu, C.M. Torok

Changes in the T2 relaxation value of the tibiofemoral articular cartilage about 6 months after anterior cruciate ligament reconstruction using the double-bundle.

MRI-Based T2 Knee Cartilage Texture Analysis Can Differentiate Subjects With and Without History of Knee Injury Despite Similar Morphological Scores:

Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures T. Baum, G.B. Joseph, D.C.

T1ρ and T2 relaxation times predict progression of knee osteoarthritis

Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral.

Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears

The epidemiology and impact of pain in osteoarthritis

Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis.

Evaluation of cartilage matrix disorders by T2 relaxation time in patients with hip dysplasia T. Nishii, M.D., H. Tanaka, M.D., N. Sugano, M.D., T. Sakai,

Early Effects of HIP Arthroscopy on Articular Cartilage Composition in Femoroacetabular Impingement Patients M.A. Samaan, A.L. Zhang, M.C. Gallo, T.M.

The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement.

Changes in social isolation and loneliness following total hip and knee arthroplasty: longitudinal analysis of the English Longitudinal Study of Ageing.

Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study A. Guermazi,

A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging – data from the Osteoarthritis Initiative C. Stehling, T. Baum,

A longitudinal study of the quantitative evaluation of patella cartilage after total knee replacement by delayed gadolinium-enhanced magnetic resonance.

Does a yoga-strengthening program for women with knee osteoarthritis have an effect on gait patterns? An investigation with principal components analysis

M. C. Gallo, C. Wyatt, V. Pedoia, D. Kumar, S. Lee, L. Nardo, T. M

Bilateral cartilage T2 mapping 9 years after Mega-OATS implantation at the knee: a quantitative 3T MRI study P.M. Jungmann, P.U. Brucker, T. Baum, T.M.

Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives Y. Henrotin Osteoarthritis and Cartilage

Automatic cartilage segmentation and measurement for diagnosis of OA using 3D box and Gaussian filters X. Cui, S. Li, M. Yu, H. Kim, K.-S. Kwack, B.-H.

Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic.

Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and.

Differences in radiographic features of knee osteoarthritis in African-Americans and Caucasians: the Johnston County Osteoarthritis Project L. Braga,

Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T.

Nondestructive assessment of sGAG content and distribution in normal and degraded rat articular cartilage via EPIC-μCT L. Xie, A.S.P. Lin, R.E. Guldberg,

B. C. Fleming, H. L. Oksendahl, W. A. Mehan, R. Portnoy, P. D

Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: the ROAD study T. Iidaka, S. Muraki, T. Akune,

J.A. Lynch, N. Parimi, R.K. Chaganti, M.C. Nevitt, N.E. Lane

Variation of radius of curvature around the femoral head and its associations with gender and incident radiographic hip osteoarthritis: Data from the.

Knee cartilage assessment with MRI (dGEMRIC) and subjective knee function in ACL injured copers: a cohort study with a 20 year follow-up P. Neuman, H.

Automatic morphometric cartilage quantification in the medial tibial plateau from MRI for osteoarthritis grading E.B. Dam, Ph.D., J. Folkesson, M.Sc.,

Subjects with higher physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis.

T. Nozaki, Y. Kaneko, H. Yu, K. Kaneshiro, R. Schwarzkopf, T. Hara, H

Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3years –

Do persons with asymmetric hip pain or radiographic hip OA have worse pain and structure outcomes in the knee opposite the more affected hip? Data from.

Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative S. Maschek,

Quantitative measurement of medial femoral knee cartilage volume – analysis of the OA Biomarkers Consortium FNIH Study cohort L.F. Schaefer, M. Sury,

A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration: data from the osteoarthritis initiative

Natural history of pain and disability among African–Americans and Whites with or at risk for knee osteoarthritis: A longitudinal study E.R. Vina, D.

Medial meniscus posterior horn zones show differing responses to static loading in subjects with knee osteoarthritis compared to controls N.E. Calixto,

Novel statistical methodology reveals that hip shape is associated with incident radiographic hip osteoarthritis among African American women H. An,

Associations between patellofemoral joint cartilage T1ρ and T2 and knee flexion moment and impulse during gait in individuals with and without patellofemoral.

X. Li, Ph. D. , C. Benjamin Ma, M. D. , T. M. Link, M. D. , D. -D

Bone marrow lesions identified by MRI in knee osteoarthritis are associated with locally increased bone mineral density measured by QCT T. Lowitz, O.

Elevated cartilage T2 and increased severity of cartilage defects at baseline are associated with the development of knee pain over 7 years G.B. Joseph,

Region of interest analysis: by selecting regions with denuded areas can we detect greater amounts of change? D.J. Hunter, L. Li, Y.Q. Zhang, S. Totterman,

D.J. Hunter Osteoarthritis and Cartilage

Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study D.K. White, C. Tudor-Locke, Y.

Synovitis and the risk of knee osteoarthritis: the MOST Study

Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score: directional fractal.

C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec

Longitudinal evaluation of T1ρ and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage J. Schooler, D. Kumar, L. Nardo, C. McCulloch,

R. B. Souza, C. Stehling, B. T. Wyman, M. -P. Hellio Le Graverand, X

D. Kumar, D. C. Karampinos, T. D. MacLeod, W. Lin, L. Nardo, X. Li, T

Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts: The ROAD study

Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study M.D. Crema, D.T. Felson, A. Guermazi,

Detection of degenerative cartilage disease: comparison of high-resolution morphological MR and quantitative T2 mapping at 3.0 Tesla S. Apprich, G.H.

B. C. Fleming, H. L. Oksendahl, W. A. Mehan, R. Portnoy, P. D

Osteoarthritis year in review 2016: mechanics

Knee pain outcomes in persons discordant for radiographic hip OA: Data from the osteoarthritis initiative G.B. Joseph, J.F. Hilton, P.M. Jungmann, J.A.

Baseline magnetic resonance imaging cartilage T2 relaxation time measurements as predictors of total knee arthroplasty in African-Americans – Data from.

Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period.

Presentation transcript:

Racial differences in biochemical knee cartilage composition between African-American and Caucasian-American women with 3 T MR-based T2 relaxation time measurements – data from the Osteoarthritis Initiative A. Yu, U. Heilmeier, M. Kretzschmar, G.B. Joseph, F. Liu, H. Liebl, C.E. McCulloch, M.C. Nevitt, N.E. Lane, T.M. Link Osteoarthritis and Cartilage Volume 23, Issue 9, Pages 1595-1604 (September 2015) DOI: 10.1016/j.joca.2015.04.023 Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Schematic illustration showing selection of subjects. 100 African-American women and 100 Caucasian-American women fulfilled the inclusion and exclusion criteria. *Subjects were matched by cohort, KL score, site, baseline age and by BMI strata, and randomly selected from the eligible knees in each stratum. Thirty-eight African-Americans failed to match. Osteoarthritis and Cartilage 2015 23, 1595-1604DOI: (10.1016/j.joca.2015.04.023) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Representative example of laminar regions of interest shown for the medial femoral cartilage. The green region corresponds to the superficial layer, while the red region corresponds to the deep cartilage layer. Osteoarthritis and Cartilage 2015 23, 1595-1604DOI: (10.1016/j.joca.2015.04.023) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Representative color-coded sagittal T2 maps showing the segmented medial femur of an African-American subject (A) and a matched Caucasian-American subject (B). Cartilage of the African-American subject (A) shows lower T2 values. Osteoarthritis and Cartilage 2015 23, 1595-1604DOI: (10.1016/j.joca.2015.04.023) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions