Coagulopathy and blood component transfusion in trauma

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Coagulopathy and blood component transfusion in trauma D.R. Spahn, R. Rossaint British Journal of Anaesthesia Volume 95, Issue 2, Pages 130-139 (August 2005) DOI: 10.1093/bja/aei169 Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 1 Simplified diagram showing the key steps of the haemostasis process. British Journal of Anaesthesia 2005 95, 130-139DOI: (10.1093/bja/aei169) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 2 The coagulation process. For explanation see text. British Journal of Anaesthesia 2005 95, 130-139DOI: (10.1093/bja/aei169) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 3 The interplay between metabolic acidosis, hypothermia and progressive coagulopathy in trauma (modified from reference 72, with permission from Excerpta Medica Inc.). British Journal of Anaesthesia 2005 95, 130-139DOI: (10.1093/bja/aei169) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 4 Fluid and blood component treatment in major bleeding (modified from reference 25, with permission from European Society of Haemapheresis). Values of various parameters represent trigger points at which relevant blood components should be transfused. RBC, red blood cells; FFP, fresh frozen plasma; PCC, prothrombin complex concentrate; Fg, fibrinogen; Plt, platelets; Hct, haematocrit; PT, prothrombin time; aPTT, activated partial thromboplastin time. British Journal of Anaesthesia 2005 95, 130-139DOI: (10.1093/bja/aei169) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions