Cardiac risk in patients undergoing carotid endarterectomy: Impact on perioperative and long-term mortality  William C. Mackey, MD, Thomas F. O'Donnell,

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Presentation transcript:

Cardiac risk in patients undergoing carotid endarterectomy: Impact on perioperative and long-term mortality  William C. Mackey, MD, Thomas F. O'Donnell, MD, Allan D. Callow, MD, PhD  Journal of Vascular Surgery  Volume 11, Issue 2, Pages 226-234 (February 1990) DOI: 10.1016/0741-5214(90)90265-C Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Comparison of life-table stroke-free rates and life-table stroke-free survival rates in our carotid endarterectomy patients. Shaded area represents nonstroke-related mortality. Journal of Vascular Surgery 1990 11, 226-234DOI: (10.1016/0741-5214(90)90265-C) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Life-table survival for patients with (group I) and without (group II) overt coronary disease. N values for each time point are shown, p < 0.0001 for group I versus group II survival. Journal of Vascular Surgery 1990 11, 226-234DOI: (10.1016/0741-5214(90)90265-C) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Life-table, myocardial infarction—free rates for patients with (group I) and without (group II) overt coronary disease. N values for each time point are shown, p = 0.0002 for difference in myocardial infarction—free rates between groups. Note similarity between myocardial infarction—free rates and survival rates (Fig. 2) within groups. Journal of Vascular Surgery 1990 11, 226-234DOI: (10.1016/0741-5214(90)90265-C) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Life-table survival for patients without overt coronary disease but with (group IIA) and without (group IIB) risk factors (diabetes, cigarette use, hyperlipidemia). N values for each time point are shown, p = 0.01 for difference between groups. Note similarity of survival up to 3 years and divergence thereafter. Journal of Vascular Surgery 1990 11, 226-234DOI: (10.1016/0741-5214(90)90265-C) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Life-table, myocardial infarction—free rates for patients without overt coronary disease but with (group IIA) and without (group IIB) risk factors (diabetes, cigarette use, hyperlipidemia). N values for each time point are shown, p = 0.024 for difference between groups. Note similarity between infarction-free and survival rates (Fig. 4) within groups. Note similarity of infarction-free rates between groups up to 3 years and divergence thereafter. Journal of Vascular Surgery 1990 11, 226-234DOI: (10.1016/0741-5214(90)90265-C) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 6 Algorithm for cardiac evaluation of carotid patients. Proof that aggressive cardiac evaluation and therapy improves late survival awaits results of prospective randomized trials. Journal of Vascular Surgery 1990 11, 226-234DOI: (10.1016/0741-5214(90)90265-C) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions