A, b, e, f) Computed tomography (CT) of the chest and c, d) positron emission tomography (PET) with 2-deoxy-2-[fluorine-18] fluoro-D-glucose (18F-FDG)

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a, b, e, f) Computed tomography (CT) of the chest and c, d) positron emission tomography (PET) with 2-deoxy-2-[fluorine-18] fluoro-D-glucose (18F-FDG) integrated with CT at the same anatomic level before (a-d) and after (e, f) cladribine therapy. a, b) Mult... a, b, e, f) Computed tomography (CT) of the chest and c, d) positron emission tomography (PET) with 2-deoxy-2-[fluorine-18] fluoro-D-glucose (18F-FDG) integrated with CT at the same anatomic level before (a-d) and after (e, f) cladribine therapy. a, b) Multiple thick-walled cysts of variable size associated with parenchymal infiltrates suggesting infiltration by inflammatory cells are visible. c, d) Increased 18F-FDG uptake by lung parenchyma is visible. e, f) Heterogeneous radiological response following cladribine therapy, with disappearance of some cysts, enlargement of others, along with decreased cyst wall thickness and resolution of parenchymal infiltrates is visible. Mouhamad Nasser et al. ERJ Open Res 2018;4:00089-2017 ©2018 by European Respiratory Society