Efficacy and Safety of Systemic Long-Term Treatments for Moderate-to-Severe Psoriasis: A Systematic Review and Meta-Analysis  Alexander Nast, Anja Jacobs, Stefanie Rosumeck, Ricardo N. Werner  Journal of Investigative Dermatology  Volume 135, Issue 11, Pages 2641-2648 (November 2015) DOI: 10.1038/jid.2015.206 Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Identification of literature. Journal of Investigative Dermatology 2015 135, 2641-2648DOI: (10.1038/jid.2015.206) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Forest plot: Verum versus placebo—PASI 75 at weeks 24–28. CI, confidence interval; b.i.d., twice daily; b.i.w., twice weekly; EOW, every other week; PASI, psoriasis area and severity index; q.w., once weekly; w, week. Journal of Investigative Dermatology 2015 135, 2641-2648DOI: (10.1038/jid.2015.206) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Forest plot: Verum versus placebo—PASI 75 at weeks 24–28. CI, confidence interval; b.i.d., twice daily; b.i.w., twice weekly; EOW, every other week; PASI, psoriasis area and severity index; q.w., once weekly; w, week. Journal of Investigative Dermatology 2015 135, 2641-2648DOI: (10.1038/jid.2015.206) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions