Volume 20, Issue 6, Pages (June 2012)

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Volume 20, Issue 6, Pages 1118-1126 (June 2012) A Position-Specific Distance-Dependent Statistical Potential for Protein Structure and Functional Study Feng Zhao, Jinbo Xu Structure Volume 20, Issue 6, Pages 1118-1126 (June 2012) DOI: 10.1016/j.str.2012.04.003 Copyright © 2012 Elsevier Ltd Terms and Conditions

Structure 2012 20, 1118-1126DOI: (10.1016/j.str.2012.04.003) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 1 Distance Dependence of DOPE and Our Potential EPAD (A) The solid curve shows the DOPE interaction potential for atom Cα in ALA and atom Cα in LEU. The other three curves show the EPAD potentials for the same atom pair in three different positions of protein 1gvp. The legend shows the native distances of this atom pair in these positions. (B) The curves show the DOPE and EPAD potentials for atom N in Cys and atom O in Trp in three different proteins of 1B3A, 1BKR, and 1PTQ. Structure 2012 20, 1118-1126DOI: (10.1016/j.str.2012.04.003) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 2 An Example Probabilistic Neural Network, in which Si and Sj Are the Sequence Profile Contexts Centered at the ith and jth Residues, Respectively Hq1 and Hp2 are the neurons in the first and second hidden layers. Structure 2012 20, 1118-1126DOI: (10.1016/j.str.2012.04.003) Copyright © 2012 Elsevier Ltd Terms and Conditions