Volume 77, Issue 9, Pages (May 2010)

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Volume 77, Issue 9, Pages 757-759 (May 2010) LECT2 amyloidosis Merrill D. Benson Kidney International Volume 77, Issue 9, Pages 757-759 (May 2010) DOI: 10.1038/ki.2010.18 Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure 1 Renal histology of LECT2 amyloidosis. (a) Renal biopsy from a patient with LECT2 amyloidosis, showing amyloid deposits in glomeruli, blood vessel walls, and tubular interstitium. (Congo red stain; original magnification, ×100.) (b) Same section as in panel a, viewed between cross-polars, showing characteristic green birefringence of amyloid. (c) Immunohistochemical staining of renal biopsy in panel a, stained with anti-LECT2 antibody by an antigen retrieval technique at pH2. It should be noted that although immunohistochemistry for LECT2 was originally described for sections from frozen tissue, formalin-fixed, paraffin-embedded tissue may require antigen retrieval techniques to give positive staining. Kidney International 2010 77, 757-759DOI: (10.1038/ki.2010.18) Copyright © 2010 International Society of Nephrology Terms and Conditions