Cost-effectiveness of the Edwards SAPIEN transcatheter heart valve compared with standard management and surgical aortic valve replacement in patients.

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Presentation transcript:

Cost-effectiveness of the Edwards SAPIEN transcatheter heart valve compared with standard management and surgical aortic valve replacement in patients with severe symptomatic aortic stenosis: A Canadian perspective Brett Doble, MSc, Gord Blackhouse, MSc, Ron Goeree, MA, Feng Xie, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 146, Issue 1, Pages 52-60.e3 (July 2013) DOI: 10.1016/j.jtcvs.2012.06.018 Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Structure of 30-day postoperative decision tree. B, Structure of long-term Markov model. SAVR, Surgical aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2013 146, 52-60.e3DOI: (10.1016/j.jtcvs.2012.06.018) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A, DSA for TF-TAVI versus SM (LYs). B, DSA for TF-TAVI versus SM (QALYs). TF-TAVI, Transfemoral transcatheter aortic valve implantation; SM, standard management; LY, life-year; QALY, quality-adjusted life-year; Can$, Canadian dollars; SAVR, surgical aortic valve replacement; ICER, incremental cost-effectiveness ratio. The Journal of Thoracic and Cardiovascular Surgery 2013 146, 52-60.e3DOI: (10.1016/j.jtcvs.2012.06.018) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 A, Cost-effectiveness acceptability curves for TF-TAVI versus SM (LYs). B, Cost-effectiveness acceptability curves for TF-TAVI versus SM (QALYs). C, Cost-effectiveness acceptability curves for TF or TA-TAVI versus SAVR (LYs). D, Cost-effectiveness acceptability curves for TF or TA-TAVI versus SAVR (QALYs). TF-TAVI, Transfemoral transcatheter aortic valve implantation; TA-TAVI, transapical transcatheter aortic valve implantation; SM, standard management; SAVR, surgical aortic valve replacement; LY, life-year; QALY, quality-adjusted life-year; Can$, Canadian dollars. The Journal of Thoracic and Cardiovascular Surgery 2013 146, 52-60.e3DOI: (10.1016/j.jtcvs.2012.06.018) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions