Predictors of Death, Local Recurrence, and Distant Metastasis in Completely Resected Pathological Stage-I Non–Small-Cell Lung Cancer Jung-Jyh Hung, MD,

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Predictors of Death, Local Recurrence, and Distant Metastasis in Completely Resected Pathological Stage-I Non–Small-Cell Lung Cancer Jung-Jyh Hung, MD, PhD, Wen-Juei Jeng, MD, Wen-Hu Hsu, MD, Teh-Ying Chou, MD, PhD, Biing-Shiun Huang, MD, PhD, Yu-Chung Wu, MD Journal of Thoracic Oncology Volume 7, Issue 7, Pages 1115-1123 (July 2012) DOI: 10.1097/JTO.0b013e31824cbad8 Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Cumulative probability of (A) overall survival and (B) disease-free survival in 756 patients with resected stage-I non–small-cell lung cancer. Journal of Thoracic Oncology 2012 7, 1115-1123DOI: (10.1097/JTO.0b013e31824cbad8) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Cumulative probability of freedom from (A) overall recurrence, (B) local recurrence, and (C) distant metastasis in 756 patients with resected stage-I non–small cell lung cancer. Journal of Thoracic Oncology 2012 7, 1115-1123DOI: (10.1097/JTO.0b013e31824cbad8) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 A, Kaplan-Meier analysis (log-rank test) for local recurrence. The patients were divided into three groups according to number of positive risk predictors (smoking index > 20 and number of mediastinal lymph nodes dissected/sampled ⩽ 15): none positive (group 1), one positive (group 2), and two positive (group 3). The possibility of local recurrence increased as the number of risk predictors increased. B, Kaplan-Meier analysis (log-rank test) for distant metastasis. The patients were divided into three groups according to number of positive risk predictors (nonsquamous cell histology and T2a): none positive (group 1), one positive (group 2), and two positive (group 3). Patients with both positive risk predictors had higher possibility of distant metastasis. Journal of Thoracic Oncology 2012 7, 1115-1123DOI: (10.1097/JTO.0b013e31824cbad8) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions