Volume 9, Issue 6, Pages 592-598 (June 2010) Effects of vaccination on onset and outcome of Dravet syndrome: a retrospective study  Anne M McIntosh, PhD, Jacinta McMahon, BSc, Leanne M Dibbens, PhD, Xenia Iona, DipBiomedSci, John C Mulley, PhD, Prof Ingrid E Scheffer, PhD, Prof Samuel F Berkovic, MD  The Lancet Neurology  Volume 9, Issue 6, Pages 592-598 (June 2010) DOI: 10.1016/S1474-4422(10)70107-1 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Timing of first seizure and DTP vaccination The Lancet Neurology 2010 9, 592-598DOI: (10.1016/S1474-4422(10)70107-1) Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 2 Schematic representation of SCN1A protein with mutations SCN1A contains four domains (I–IV) each with six transmembrane segments. Segment four is the voltage sensor (blue) and segments five and six form the ion channel pore (grey). Truncation mutations (blue squares), missense mutations (red circles), and splice site mutations (green triangles) are shown. The exon 21–26 deletion identified in one patient is shown at the site that the deletion begins (green diamond). The Lancet Neurology 2010 9, 592-598DOI: (10.1016/S1474-4422(10)70107-1) Copyright © 2010 Elsevier Ltd Terms and Conditions