Multiple Ground-Glass Opacity in Metastasis of Malignant Melanoma Diagnosed By Lung Biopsy  Riki Okita, MD, Motohiro Yamashita, MD, Masao Nakata, MD,

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Multiple Ground-Glass Opacity in Metastasis of Malignant Melanoma Diagnosed By Lung Biopsy  Riki Okita, MD, Motohiro Yamashita, MD, Masao Nakata, MD, Norihiro Teramoto, MD, Akihiro Bessho, MD, Hiroshi Mogami, MD  The Annals of Thoracic Surgery  Volume 79, Issue 1, Pages e1-e2 (January 2005) DOI: 10.1016/j.athoracsur.2004.03.096

Fig 1 (A) A high-resolution computed tomography showing multiple ground-glass opacity lesions in the bilateral lungs. (B) Biopsied lesion. (C–E) A ground-glass opacity lesion showed S-100-positive metastatic melanoma cells lined in a lepidic pattern beneath keratin-7-positive normal alveolar epithelium simulating bronchioloalveolar carcinoma. (C) Hematoxylin & eosin ×100 before reduction. (D) Keratin-7 ×400 before reduction. (E) S-100 ×400 before reduction. The Annals of Thoracic Surgery 2005 79, e1-e2DOI: (10.1016/j.athoracsur.2004.03.096)