Lobe-specific extent of systematic lymph node dissection for non–small cell lung carcinomas according to a retrospective study of metastasis and prognosis 

Slides:



Advertisements
Similar presentations
Results of Initial Operations in Non–Small Cell Lung Cancer Patients With Single-Level N2 Disease  Yasuhiko Ohta, MD, Yosuke Shimizu, MD, Hiroshi Minato,
Advertisements

Vascular endothelial growth factor expression in non-small-cell lung cancer: Prognostic significance in squamous cell carcinoma  Hideyuki Imoto, MD, Toshihiro.
Stephen R. Broderick, MD, MPHS 
Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.
Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer  Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.
Effect of tumor size on prognosis in patients with non–small cell lung cancer: The role of segmentectomy as a type of lesser resection  Morihito Okada,
Yih-Leong Chang, MD, Chen-Tu Wu, MD, Yung-Chie Lee, MD, PhD 
Preoperative mediastinoscopic assessment of N factors and the need for mediastinal lymph node dissection in T1 lung cancer  Takeshi Funatsu, MD, Yoshito.
Prognostic evaluation based on a new TNM staging system proposed by the International Association for the Study of Lung Cancer for resected non–small.
Prognostic factors and survival after complete resection of pulmonary metastases from colorectal carcinoma: Experiences in 167 patients  Joachim Pfannschmidt,
Prognosis and survival after resection for bronchogenic carcinoma based on the 1997 TNM-staging classification: the Japanese experience  Tsuguo Naruke,
Role of lymphatic invasion in the prognosis of patients with clinical node-negative and pathologic node-positive lung adenocarcinoma  Takahiro Mimae,
Tumors of the esophagogastric junction
Factors predictive of prognosis after esophagectomy for squamous cell cancer  Houhuai Li, MD, PhD, Qingzhen Zhang, Lin Xu, MD, Yijiang Chen, Yongxiang.
Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer  Robert E. Merritt, MD, Chuong D. Hoang, MD,
Mediastinal Nodal Involvement in Patients with Clinical Stage I Non–Small-Cell Lung Cancer: Possibility of Rational Lymph Node Dissection  Tomohiro Haruki,
Pattern of lymphatic spread in thoracic esophageal squamous cell carcinoma: A single- institution experience  Bin Li, MD, Haiquan Chen, MD, Jiaqing Xiang,
The Impact of Superior Mediastinal Lymph Node Metastases on Prognosis in Non-small Cell Lung Cancer Located in the Right Middle Lobe  Yukinori Sakao,
Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.
Survival related to lymph node involvement in lung cancer after sleeve lobectomy compared with pneumonectomy  Morihito Okada, MD, Hiroyuki Yamagishi,
Boundary between N1 and N2 Lymph Node Descriptors in the Subcarinal Zone in Lower Lobe Lung Cancer: A Brief Report  Mitsuhiro Isaka, MD, Haruhiko Kondo,
Combined Resection of Superior Vena Cava for Lung Carcinoma: Prognostic Significance of Patterns of Superior Vena Cava Invasion  Kenji Suzuki, MD, Hisao.
Predictors of Death, Local Recurrence, and Distant Metastasis in Completely Resected Pathological Stage-I Non–Small-Cell Lung Cancer  Jung-Jyh Hung, MD,
Ugo Pastorino, MD, Marc Buyse, ScD, Godehard Friedel, MD, Robert J
Mediastinal Lymph Node Examination and Survival in Resected Early-Stage Non– Small-Cell Lung Cancer in the Surveillance, Epidemiology, and End Results.
Large cell neuroendocrine carcinoma and large cell carcinomas with neuroendocrine morphology of the lung: prognosis after complete resection and systematic.
Prognostic factors in clinical stage I non–small cell lung cancer
Lorenzo Spaggiari, MD, PhD, Ugo Pastorino, MD 
Proposed Revision Of The Staging Classification For Esophageal Cancer
Large cell neuroendocrine carcinoma of the lung: A clinicopathologic study of eighty- seven cases  Hidefumi Takei, MDa,b, Hisao Asamura, MDb, Arafumi Maeshima,
A clinicopathological study of resected subcentimeter lung cancers: a favorable prognosis for ground glass opacity lesions  Hisao Asamura, MD, Kenji Suzuki,
Primary repair of rupture of a main and lobar bronchus
Support Your Specialty
Results of surgical intervention for p-stage IIIA (N2) non–small cell lung cancer: Acceptable prognosis predicted by complete resection in patients with.
Prognostic assessment of 1310 patients with non–small-cell lung cancer who underwent complete resection from 1980 to 1993  Kunihiko Inoue, MDa, Masami.
Prolonged survival in patients with resected non–small cell lung cancer and single-level N2 disease  Steven M Keller, MD, Mark G Vangel, PhD, Henry Wagner,
Reasonable Extent of Lymph Node Dissection in Intentional Segmentectomy for Small- Sized Peripheral Non–Small-Cell Lung Cancer: From the Clinicopathological.
Is surgery for multiple lung metastases reasonable
Stephen R. Broderick, MD, MPHS 
Pulmonary Resection in Patients Aged 80 Years or Over with Clinical Stage I Non-small Cell Lung Cancer: Prognostic Factors for Overall Survival and Risk.
Pathologic N1 non-small cell lung cancer: Correlation between pattern of lymphatic spread and prognosis  Alessandro Marra, MD, PhD, Ludger Hillejan, MD,
Results of surgical treatment of non–small cell lung cancer: validation of the new postoperative pathologic tnm classification  Jacek Jassem, MDa, Jan.
Superior and Basal Segment Lung Cancers in the Lower Lobe Have Different Lymph Node Metastatic Pathways and Prognosis  Shun-ichi Watanabe, MD, Kenji Suzuki,
Multiple Primary Cancers or Multiple Metastases, That Is the Question
Yuji Tachimori, MD, Hoichi Kato, MD, Hiroshi Watanabe, MD 
It’s All in the “Swerve of the Curve”
Value of systematic mediastinal lymph node dissection during pulmonary metastasectomy  Florian Loehe, MD, Sonja Kobinger, MD, Rudolf A Hatz, MD, Thomas.
“Early” peripheral lung cancer: prognostic significance of ground glass opacity on thin- section computed tomographic scan  Kenji Suzuki, MD, Hisao Asamura,
Prognosis of Resected Non-Small Cell Lung Cancer Patients with Intrapulmonary Metastases  Kanji Nagai, MD, Yasunori Sohara, MD, Ryosuke Tsuchiya, MD,
Distribution and Likelihood of Lymph Node Metastasis Based on the Lobar Location of Nonsmall-Cell Lung Cancer  Robert J. Cerfolio, MD, Ayesha S. Bryant,
Lymph Node Metastasis In Small Peripheral Adenocarcinoma Of The Lung
A Strategy for Determining Which Thoracic Esophageal Cancer Patients Should Undergo Cervical Lymph Node Dissection  Shiro Nagatani, MD, Yutaka Shimada,
Carcinoma of the esophagus: Prognostic significance of histologic type
Low-grade fibromyxoid sarcoma arising in the mediastinum
Problems related to TNM staging: Patients with stage III non–small cell lung cancer  Kotaro Kameyama, MD, Cheng-long Huang, MD, Dage Liu, MD, Taku Okamoto,
Superior sulcus lung tumors: Impact of local control on survival
Second operation for upper mediastinal lymphadenopathy after complete resection for cancer of the left lung  Masami Sato, MDa, b, Teruaki Koike, MDa,
Neal S Goldstein, MD  The Annals of Thoracic Surgery 
Immediate and Long-Term Survival After Surgery for Lung Cancer in Heart Transplant Recipients  Patrick Bagan, MD, Jalal Assouad, MD, Pascal Berna, MD,
Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer  Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.
Mediastinal lymph node dissection improves survival in patients with stages II and IIIa non-small cell lung cancer  Steven M Keller, MD, Sudeshna Adak,
Nonanatomic prognostic factors in resected nonsmall cell lung carcinoma: the importance of perineural invasion as a new prognostic marker  Adnan Sayar,
Results of Initial Operations in Non–Small Cell Lung Cancer Patients With Single-Level N2 Disease  Yasuhiko Ohta, MD, Yosuke Shimizu, MD, Hiroshi Minato,
Left Pneumonectomy for Lung Cancer After Correction of Contralateral Partial Anomalous Pulmonary Venous Return  Hiroyuki Sakurai, MD, Haruhiko Kondo,
Mark I. Block, MD  The Annals of Thoracic Surgery 
Completely Resected Non-Small Cell Lung Cancer: Reconsidering Prognostic Value and Significance of N2 Metastases  Marc Riquet, MD, PhD, Patrick Bagan,
Is there a benefit to continuing with resection of all sites of disease when clinically occult pleural metastases from non–small cell carcinoma are found? 
Prognostic factors for survival after pulmonary resection of metastatic renal cell carcinoma  Joachim Pfannschmidt, MD, Hans Hoffmann, MD, PhD, Thomas.
Long-Term Results of Sleeve Lobectomy in the Management of Non–Small Cell Lung Carcinoma and Low-Grade Neoplasms  Robert E. Merritt, MD, Douglas J. Mathisen,
Reappraise the advanced technique for tumor localization and sentinel lymph node assessment in clinical early-stage non–small cell lung cancer  Chengwu.
Presentation transcript:

Lobe-specific extent of systematic lymph node dissection for non–small cell lung carcinomas according to a retrospective study of metastasis and prognosis  Hisao Asamura, MD, Haruhiko Nakayama, MD, Haruhiko Kondo, MD, Ryosuke Tsuchiya, MD, Tsuguo Naruke, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 117, Issue 6, Pages 1102-1111 (June 1999) DOI: 10.1016/S0022-5223(99)70246-1 Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 Survival curve for all 166 patients with lung carcinoma with mediastinal lymph node metastasis. Five-year survival was 35%. Numbers in parentheses indicate number of patients still at risk at every postoperative year. The Journal of Thoracic and Cardiovascular Surgery 1999 117, 1102-1111DOI: (10.1016/S0022-5223(99)70246-1) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 2 Survival curves of patients with single-station metastases (MET) and multiple-station metastases. Five-year survivals for patients with single-station metastases and multiple-station metastases were 48% and 18%, respectively. Statistically significant difference between groups was observed (log rank test, P = .0006). Numbers in parentheses indicate number of patients still at risk at every postoperative year. The Journal of Thoracic and Cardiovascular Surgery 1999 117, 1102-1111DOI: (10.1016/S0022-5223(99)70246-1) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 3 Survival curves of patients with single-node metastases (MET) and multiple-node metastases. Five-year survivals for patients with single-node metastases and multiple-node metastases were 55% and 20%, respectively. Statistically significant difference between groups was observed (log rank test, P = .0002). Numbers in parentheses indicate number of patients still at risk at every postoperative year. The Journal of Thoracic and Cardiovascular Surgery 1999 117, 1102-1111DOI: (10.1016/S0022-5223(99)70246-1) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 4 Survival curves of patients with and without subcarinal node (station 7) metastases among 54 patients with right upper lobe (RUL) tumors. There was no statistically significant difference between groups (log rank test, P = .97). Numbers in parentheses indicate number of patients still at risk at every postoperative year. The Journal of Thoracic and Cardiovascular Surgery 1999 117, 1102-1111DOI: (10.1016/S0022-5223(99)70246-1) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 5 Survival curves of patients with and without superior mediastinal node metastasis (from station 1 through station 4) in 41 right lower lobe tumors. Five-year survival for patients with superior mediastinal metastasis was 4.1%. There was no statistically significant difference (log rank test, P = .55). Numbers in parentheses indicate the number of patients still at risk at every 1 year after surgery. The Journal of Thoracic and Cardiovascular Surgery 1999 117, 1102-1111DOI: (10.1016/S0022-5223(99)70246-1) Copyright © 1999 Mosby, Inc. Terms and Conditions