Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma Bradley E. Chipps, MD, Stanley J. Szefler,

Slides:

Advertisements

Similar presentations

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Advertisements

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

What drives prescription patterns in pediatric asthma management?

Anne M. Fitzpatrick, PhD, MSCR, W. Gerald Teague, MD

Effects of time, albuterol, and budesonide on the shape of the flow-volume loop in children with asthma Anand C. Patel, MD, Mark L. Van Natta, MHS, James.

Fatty acids, inflammation, and asthma

A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma L. Keoki Williams, MD, MPH,

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Advances in pediatric asthma in 2011: Moving forward

Is 9 more than 2 also in allergic airway inflammation?

Fatty acids, inflammation, and asthma

Advancing asthma care: The glass is only half full!

Keith J. Simons, PhD, Margherita Strolin Benedetti, PhD, F. Estelle R

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Katherine A. Vierk, MPH, Kathleen M. Koehler, PhD, MPH, Sara B

Impact of Asthma Exacerbations and Asthma Triggers on Asthma-related Quality of Life in Patients with Severe or Difficult-to-Treat Asthma Allan T. Luskin,

Test for Respiratory and Asthma Control in Kids (TRACK): A caregiver-completed questionnaire for preschool-aged children Kevin R. Murphy, MD, Robert.

Asthma Exacerbations and Triggers in Children in TENOR: Impact on Quality of Life Bradley E. Chipps, MD, Tmirah Haselkorn, PhD, Karin Rosén, MD, PhD,

Physician needs in health informatics: Just ask the docs

Treatment of chronic autoimmune urticaria with omalizumab

Elina Jerschow, MD, MSc, Robert Y. Lin, MD, MSc, Moira M

Peter M. Wolfgram, MD, David B. Allen, MD

William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P

Consistently very poorly controlled asthma is associated with greater activity and school impairment in children with severe or difficult-to-treat asthma

Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA

Serum tryptase levels in atopic and nonatopic children

Peter König, MD, PhD Journal of Allergy and Clinical Immunology

Reply Journal of Allergy and Clinical Immunology

Acute asthma intervention: Insights from the STAY study

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study Bradley E.

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Biosimilars and drug development in allergic and immunologic diseases

Christian Hennig, MD, Christine Happle, MD, Gesine Hansen, MD

Increasing rate of hospitalizations for food-induced anaphylaxis in Italian children: An analysis of the Italian Ministry of Health database Rita Nocerino,

A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Claus Bachert, MD, PhD, Cezmi A. Akdis, MD

Update on the role of prostaglandins in allergic lung inflammation: Separating friends from foes, harder than you might think Martin L. Moore, PhD, R.

What is an “eosinophilic phenotype” of asthma?

Medication use in children with asthma in Finland from 1995 to 2006

The widening black/white gap in asthma hospitalizations and mortality

H. William Kelly, PharmD Journal of Allergy and Clinical Immunology

Autophagy: Nobel Prize 2016 and allergy and asthma research

News & Notes Journal of Allergy and Clinical Immunology

The Editors' Choice Journal of Allergy and Clinical Immunology

Advances in the approach to the patient with food allergy

Diagnosis and management of early asthma in preschool-aged children

Mary F. Linehan, PhD, Timothy L. Frank, MD, Michelle L

Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe.

One step forward, 2 steps back: The enigma of preschool wheeze

Risk of oral food challenges

The Editors' Choice Journal of Allergy and Clinical Immunology

Jessica H. Savage, MD, MHS, Elizabeth C. Matsui, MD, MHS, Robert A

Asthma progression: Can we and should we measure it?

The Editors' Choice Journal of Allergy and Clinical Immunology

Severity assessment in asthma: An evolving concept

Challenges in assessing outcomes for pediatric asthma

National trends in asthma visits and asthma pharmacotherapy,

Macrolide antibiotics and asthma treatment

Budesonide Inhalation Suspension Versus Montelukast in Children Aged 2 to 4 Years with Mild Persistent Asthma Stanley J. Szefler, MD, Lars-Goran Carlsson,

News Beyond Our Pages Journal of Allergy and Clinical Immunology

Asthma: The past, future, environment, and costs

Personal and parental nativity as risk factors for food sensitization

Environmental factors and eosinophilic esophagitis

Advances in pediatric asthma in 2007

Negative affect, medication adherence, and asthma control in children

Natural history of cow’s milk allergy

The Editors’ Choice Journal of Allergy and Clinical Immunology

Primary prevention of asthma and allergy

Presentation transcript:

Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma Bradley E. Chipps, MD, Stanley J. Szefler, MD, F. Estelle R. Simons, MD, Tmirah Haselkorn, PhD, David R. Mink, MS, Yamo Deniz, MD, June H. Lee, MD Journal of Allergy and Clinical Immunology Volume 119, Issue 5, Pages 1156-1163 (May 2007) DOI: 10.1016/j.jaci.2006.12.668 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 HCU by number of long-term controller medications in patients aged 6-11 years (left panel) and 12-17 years (right panel). Long-term controllers included inhaled corticosteroids, long-acting β-agonists, leukotriene modifiers, methylxanthines, and cromolyn sodium or nedocromil. No statistically significant differences were found in rates of HCU by number of long-term controllers. Journal of Allergy and Clinical Immunology 2007 119, 1156-1163DOI: (10.1016/j.jaci.2006.12.668) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Medication use by age category. ∗Based on test for linear trend, a statistically significant age trend (P < .05) was observed for methylxanthines and long-acting β-agonists. Journal of Allergy and Clinical Immunology 2007 119, 1156-1163DOI: (10.1016/j.jaci.2006.12.668) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Height and weight for age in male (left panel) and female (right panel) pediatric and adolescent patients in TENOR. ∗Differences across height for age categories in females are statistically significant, P = .0062. Journal of Allergy and Clinical Immunology 2007 119, 1156-1163DOI: (10.1016/j.jaci.2006.12.668) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Prebronchodilator (left panel) and postbronchodilator (right panel) spirometry measures in male and female pediatric and adolescent patients in TENOR. Predicted values were calculated using formulas of Wang et al9 and Hsu et al.10 Based on test for linear trend, spirometry values are statistically significant (P < .05) across age categories. Journal of Allergy and Clinical Immunology 2007 119, 1156-1163DOI: (10.1016/j.jaci.2006.12.668) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions