Polypectomy may be adequate treatment for adenoma-like dysplastic lesions in chronic ulcerative colitis Marc Engelsgjerd*, Francis A. Farraye‡,§, Robert.

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Polypectomy may be adequate treatment for adenoma-like dysplastic lesions in chronic ulcerative colitis Marc Engelsgjerd*, Francis A. Farraye‡,§, Robert D. Odze* Gastroenterology Volume 117, Issue 6, Pages 1288-1294 (December 1999) DOI: 10.1016/S0016-5085(99)70278-7 Copyright © 1999 American Gastroenterological Association Terms and Conditions

Fig. 1 (A) Endoscopic photograph of a small (<1.0 cm) sessile adenoma-like DALM in a patient with CUC. This polyp was located within an area of histologically confirmed chronic inactive colitis. The patient underwent a polypectomy and had no evidence of neoplasia at 4.2-year follow-up. (B) Histological appearance of the polyp shown in A. The lesion shows a tubular arrangement of dysplastic epithelium similar to a non–CUC-related sporadic adenoma. The epithelium is composed of basally oriented, slightly pseudostratified cells with pencil-shaped hyperchromatic nuclei, increased mitotic figures, mucin depletion, and a lack of surface maturation, all typical features of low-grade dysplasia. All of the epithelium in this photograph is dysplastic (H&E; original magnification 200×). Gastroenterology 1999 117, 1288-1294DOI: (10.1016/S0016-5085(99)70278-7) Copyright © 1999 American Gastroenterological Association Terms and Conditions

Fig. 1 (A) Endoscopic photograph of a small (<1.0 cm) sessile adenoma-like DALM in a patient with CUC. This polyp was located within an area of histologically confirmed chronic inactive colitis. The patient underwent a polypectomy and had no evidence of neoplasia at 4.2-year follow-up. (B) Histological appearance of the polyp shown in A. The lesion shows a tubular arrangement of dysplastic epithelium similar to a non–CUC-related sporadic adenoma. The epithelium is composed of basally oriented, slightly pseudostratified cells with pencil-shaped hyperchromatic nuclei, increased mitotic figures, mucin depletion, and a lack of surface maturation, all typical features of low-grade dysplasia. All of the epithelium in this photograph is dysplastic (H&E; original magnification 200×). Gastroenterology 1999 117, 1288-1294DOI: (10.1016/S0016-5085(99)70278-7) Copyright © 1999 American Gastroenterological Association Terms and Conditions