Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and.

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Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and non-enhanced imaging F.W. Roemer, H. Khrad, D. Hayashi, H. Jara, A. Ozonoff, A.K. Fotinos-Hoyer, A. Guermazi Osteoarthritis and Cartilage Volume 18, Issue 8, Pages 1062-1066 (August 2010) DOI: 10.1016/j.joca.2010.05.006 Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 (A) Sagittal PD-w FS image depicts an ill-defined hyperintense area in the weight-bearing region of the medial femoral condyle representing a BML (arrows). Note adjacent superficial cartilage damage (no arrows) (B) Same PD-w FS image shows manually segmented lesion in green. (C) The same BML is visualized with similar size on a sagittal T1-w FS CE image (arrows). (D) Manual segmentation of the same BML on sagittal T1-w FS CE image (green). (E) Same BML appears much smaller on non-FS T1-w image (black arrows). (F) Manual segmentation of BML on non-FS T1-w image (green). Osteoarthritis and Cartilage 2010 18, 1062-1066DOI: (10.1016/j.joca.2010.05.006) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Comparison of BML volumes measured on different sequences. Blue line depicts correlation between PD-w FS (x-axis) and T1-w FS CE (y-axis) sequences. Orange line shows the correlation of PD-w FS (x-axis) and non-FS T1-w (y-axis) sequences. Osteoarthritis and Cartilage 2010 18, 1062-1066DOI: (10.1016/j.joca.2010.05.006) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions