The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System M.E.A. de Kraker, V. Jarlier,

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The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System M.E.A. de Kraker, V. Jarlier, J.C.M. Monen, O.E. Heuer, N. van de Sande, H. Grundmann Clinical Microbiology and Infection Volume 19, Issue 9, Pages 860-868 (September 2013) DOI: 10.1111/1469-0691.12028 Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Trends in the total number of Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Enterococcus faecium and Enterococcus faecalis bacteraemia isolates reported to the European Antimicrobial Resistance Surveillance System between 2002 and 2008. Only laboratories that consistently reported for all years were included. Clinical Microbiology and Infection 2013 19, 860-868DOI: (10.1111/1469-0691.12028) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Total number of Escherichia coli bacteraemia isolates with different resistance phenotypes reported to the European Antimicrobial Resistance Surveillance System between 2002 and 2008. Only laboratories that consistently reported for all years were included. R = resistance; G3C = third-generation cephalosporins; FQ = fluoroquinolones; amipn = aminopenicillins. For reasons of clarity, combined resistance proportions for aminoglycosides are exclusively displayed in a Table. Clinical Microbiology and Infection 2013 19, 860-868DOI: (10.1111/1469-0691.12028) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Relative increase in the number of Escherichia coli bacteraemia isolates with different resistance phenotypes (index year = 2002) reported to the European Antimicrobial Resistance Surveillance System between 2002 and 2008. Only laboratories that consistently reported for all years were included. Symbols indicate ascertained values and lines are based on generalized linear models with Poisson distribution. Numbers and the average annual increase per phenotype are displayed in the table. R = resistance; G3C = third-generation cephalosporins; FQ = fluoroquinolones; amino = aminoglycosides; amipn = aminopenicillins. Clinical Microbiology and Infection 2013 19, 860-868DOI: (10.1111/1469-0691.12028) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions