Elevated Preoperative Hemoglobin A1c Level is Associated With Reduced Long-Term Survival After Coronary Artery Bypass Surgery Michael E. Halkos, MD,

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Presentation transcript:

Elevated Preoperative Hemoglobin A1c Level is Associated With Reduced Long-Term Survival After Coronary Artery Bypass Surgery Michael E. Halkos, MD, Omar M. Lattouf, MD, PhD, John D. Puskas, MD, Patrick Kilgo, MS, William A. Cooper, MD, Cullen D. Morris, MD, Robert A. Guyton, MD, Vinod H. Thourani, MD The Annals of Thoracic Surgery Volume 86, Issue 5, Pages 1431-1437 (November 2008) DOI: 10.1016/j.athoracsur.2008.06.078 Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier 5-year overall survival by hemoglobin A1c (HbA1c) stratification: 7.0% or greater (light line) versus less than 7.0% (heavy line). At 5 years, 87.6% of patients with HbA1c less than 7.0% survived, compared with 82.3% of patients with HbA1c of 7.0% or greater (p = 0.001). The Annals of Thoracic Surgery 2008 86, 1431-1437DOI: (10.1016/j.athoracsur.2008.06.078) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier 5-year overall survival by diabetes mellitus status. At 5 years, 89.8% of patients without diabetes (light line) survived, compared with 81.1% of patients with diabetes (heavy line; p < 0.001). The Annals of Thoracic Surgery 2008 86, 1431-1437DOI: (10.1016/j.athoracsur.2008.06.078) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier 5-year overall survival among patients with diagnosis of diabetes mellitus according to hemoglobin A1c (HbA1c) less than 7.0% (heavy line) versus 7.0% or greater (light line). Among diabetic patients, there was no significant difference in 5-year survival according to HbA1c less than 7.0% versus 7.0% or greater (p = 0.37). The Annals of Thoracic Surgery 2008 86, 1431-1437DOI: (10.1016/j.athoracsur.2008.06.078) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan-Meier 5-year overall survival among patients with diagnosis of diabetes mellitus according to treatment method: insulin therapy (light line) versus no insulin therapy (heavy line). At 5 years, 78.3% of diabetic patients treated with insulin survived, compared with 82.4% of diabetic patients treated without insulin (p = 0.006). The Annals of Thoracic Surgery 2008 86, 1431-1437DOI: (10.1016/j.athoracsur.2008.06.078) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions