Survival of mice after infection with M

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Presentation transcript:

Survival of mice after infection with M Survival of mice after infection with M. tuberculosis Beijing strains of modern and ancient sublineages. Survival of mice after infection with M. tuberculosis Beijing strains of modern and ancient sublineages. C57BL/6 mice were i.t. infected with low doses (102 CFU) (A) and high doses (2.5 × 103 CFU) (B) of each strain and observed for 320 days and 150 days, respectively. The data were obtained in three independent experiments with 10 to 15 mice in each group. Kaplan-Meier curves and log rank test were used to evaluate statistical significance. Statistically significant differences between each group infected with the individual clinical isolate and the group infected with strain H37Rv are presented. Three different patterns of animal survival are indicated (pattern I, II, and III). Simone C. M. Ribeiro et al. J. Clin. Microbiol. 2014; doi:10.1128/JCM.00498-14