M. Watanabe, MD, K. Natsuga, MD, PhD, M. Ota, MD, PhD, K. Ito, MD, PhD 

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Pyoderma Gangrenosum Associated with Acute Respiratory Distress Syndrome  M. Watanabe, MD, K. Natsuga, MD, PhD, M. Ota, MD, PhD, K. Ito, MD, PhD  The American Journal of Medicine  Volume 129, Issue 2, Pages e17-e18 (February 2016) DOI: 10.1016/j.amjmed.2015.08.035 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure Clinical manifestations of the left lower extremity, and X-ray and computed tomography images of the chest. (A) Painful deep ulcers with necrotic tissue and diffuse erosive purpura. (B) A butterfly shadow indicating pulmonary edema. (C) Ground-glass opacity and infiltrative shadows around bilateral hilar regions, thickening of interlobular septa, and bilateral pleural effusions are observed. (D) After methylprednisolone pulse treatment, the ulcers expanded with massive necrotic tissue. (E) After 11 months of treatment the ulcers have fully healed, with distinguishable scars reaching the muscles. The American Journal of Medicine 2016 129, e17-e18DOI: (10.1016/j.amjmed.2015.08.035) Copyright © 2016 Elsevier Inc. Terms and Conditions