From Static to Dynamic Risk Prediction: Time Is Everything

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Presentation transcript:

From Static to Dynamic Risk Prediction: Time Is Everything Tom Greene, PhD  American Journal of Kidney Diseases  Volume 69, Issue 4, Pages 492-494 (April 2017) DOI: 10.1053/j.ajkd.2017.01.004 Copyright © 2017 Terms and Conditions

Figure 1 The left-hand tail of each blue arrow represents the time point from which predictions are made (denoted in text as t), and the arrow length represents the time horizon over which the event probability is calculated (denoted in text as Δ). The dashed orange lines represent the time interval over which past data are available, which can be used in the prediction of future event probabilities. (Top panel) The static Cox model allows prediction of event probabilities over any time horizon from a fixed baseline defined by time 0. (Middle panel) The time-dependent Cox model allows estimation of the current risk (or future risk over a short time horizon) using information available at any time point. (Bottom panel) The dynamic regression approach allows prediction of event probabilities over any time horizon using information available at any time point. American Journal of Kidney Diseases 2017 69, 492-494DOI: (10.1053/j.ajkd.2017.01.004) Copyright © 2017 Terms and Conditions