Transplantation of initially rejected donor lungs after ex vivo lung perfusion Andreas Wallinder, MD, Sven-Erik Ricksten, MD, PhD, Christoffer Hansson,

Slides:

Advertisements

Similar presentations

Marcelo Cypel, MD, MSc, Jonathan C

Advertisements

Max B. Mitchell, MD The Journal of Thoracic and Cardiovascular Surgery

Lost in translation The Journal of Thoracic and Cardiovascular Surgery

Manuel J. Antunes, MD, PhD, DSc

Lobar lung transplantation: One size fits all

Experience from the Thoracic Surgery Residents Association traveling fellowship: Adult and pediatric lung transplantation in Toronto Taufiek Konrad Rajab,

New logos The Journal of Thoracic and Cardiovascular Surgery

Ex Vivo Lung Perfusion CHEST

Yesterday's heroic measure is now standard procedure: Extracorporeal membrane oxygenation as a bridge to lung transplant Victor van Berkel, MD, PhD

Pablo G. Sanchez, MD, PhD, Keshava Rajagopal, MD, PhD, Si M

Improving long-term survival by preventing early complications after lung transplantation: Can we prevent ripples by keeping pebbles out of the water?

Ex Vivo Evaluation of Nonacceptable Donor Lungs

Venovenous extracorporeal membrane oxygenation using a single cannula in patients with pulmonary hypertension and atrial septal defects Jeffrey Javidfar,

Ex vivo rehabilitation of non–heart-beating donor lungs in preclinical porcine model: Delayed perfusion results in superior lung function Daniel P. Mulloy,

Hemoconcentration in ex vivo lung perfusion: A case report of a novel technique used in clinical lung transplantation Andreas Wallinder, MD, Christoffer.

Centers for Disease Control “increased-risk” organ donor: Not so risky? Francis D. Pagani, MD, PhD The Journal of Thoracic and Cardiovascular Surgery

Glutathione improves the function of porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution Sebastian-P. Sommer, MD,

Form ever follows function

William M. DeCampli, MD, PhD

The protective effect of prone lung position on ischemia–reperfusion injury and lung function in an ex vivo porcine lung model Hiromichi Niikawa, MD,

The lord of the rings Antonio Miceli, MD, PhD

Conduit conundrum: If not two, why three?

Metastasectomy in a lung graft using high-flow venovenous extracorporeal lung support in a patient after single lung transplantation Bassam Redwan, MD,

Aditya K. Kaza, MD The Journal of Thoracic and Cardiovascular Surgery

Rohit K. Singal, MD, MSc, FRCSC, Rakesh C. Arora, MD, PhD, FRCSC

Abdul Rahman Dakkak, MD, Angelo M. Dell'Aquila, MD, Juergen R

It's not “just a shunt” but sometimes it should be…

Bartley P. Griffith, MD, FACS, FRCS

The bad guy, good guy scenario with a scimitar sword: A case to learn from Hani K. Najm, MD, MSc The Journal of Thoracic and Cardiovascular Surgery

Experience from an American Association for Thoracic Surgery Foundation for Thoracic Surgery Training Fellowship: Lung transplantation in Toronto General.

Ex Vivo Lung Perfusion Marcelo Cypel, MD, MSc, Shaf Keshavjee, MD, MSc

A first start for lung transplantation?

Ashok Muniappan, MD The Journal of Thoracic and Cardiovascular Surgery

The evolution of intraoperative support in lung transplantation: Cardiopulmonary bypass to extracorporeal membrane oxygenation P. Michael McFadden, MD,

Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD

Jason M. Gauthier, MD, Ruben G. Nava, MD, Daniel Kreisel, MD, PhD

Jeevanantham Rajeswaran, PhD, Eugene H. Blackstone, MD

Derrick Y. Tam, MD, Stephen E. Fremes, MD, MSc

David L. Joyce, MD The Journal of Thoracic and Cardiovascular Surgery

Leora B. Balsam, MD, Abe DeAnda, MD

Internal validation of risk models in lung resection surgery: Bootstrap versus training- and-test sampling Alessandro Brunelli, MD, Gaetano Rocco, MD

The Ross procedure: Time to reevaluate the guidelines

Video-assisted resection for lung cancer results in fewer complications Lunxu Liu, PhD, MD, FRCS The Journal of Thoracic and Cardiovascular Surgery

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Who is your plastic surgeon

Unilateral lung transplantation using right and left upper lobes: An experimental study Hitoshi Nishikawa, MD, Takahiro Oto, MD, PhD, Shinji Otani, MD,

Shunt right or left? Decision 2016

Innovation in cardiothoracic surgical training

Jason J. Han, MD, Pavan Atluri, MD

The origins of open heart surgery at the University of Minnesota 1951 to 1956 Richard A. DeWall, MD The Journal of Thoracic and Cardiovascular Surgery

The Journal of Thoracic and Cardiovascular Surgery

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

The future of cardiac surgery training: A survival guide

The patent internal thoracic artery graft: Increased degree of difficulty for left-sided pulmonary resections Robbin G. Cohen, MD, MMM The Journal of.

Should it stay or should it go?

“The more things change…”: The challenges ahead

Toward a more rational approach in treating type B aortic dissection

Energized lung resections

Preoperative PFTs: The answer is blowing in the wind

Of mice and men… The Journal of Thoracic and Cardiovascular Surgery

Did you like Terminator 3 better than Terminator 2

Samuel Kim, MD The Journal of Thoracic and Cardiovascular Surgery

A good chimney requires a good sweep

Commentary: Evaluation of primary graft dysfunction after lung transplantation—It is time to teach an old dog new tricks! W. Hampton Gray, MD, P. Michael.

Edward Y. Chan, MD, Michael J. Reardon, MD

Marcelo Cypel, MD, MSc, Jonathan C

Use of a low-resistance compliant thoracic artificial lung in the pulmonary artery to pulmonary artery configuration Christopher N. Scipione, MD, Rebecca.

Zipping up after a median sternotomy: Are we at the end of the wire?

Deciding how much to pay for effective care

Presentation transcript:

Transplantation of initially rejected donor lungs after ex vivo lung perfusion Andreas Wallinder, MD, Sven-Erik Ricksten, MD, PhD, Christoffer Hansson, MSc, Gerdt C. Riise, MD, PhD, Martin Silverborn, MD, PhD, Hans Liden, MD, PhD, Michael Olausson, MD, PhD, Göran Dellgren, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 144, Issue 5, Pages 1222-1228 (November 2012) DOI: 10.1016/j.jtcvs.2012.08.011 Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Schematic drawing of the ex vivo lung perfusion unit. The blood enters the open reservoir via the remnant of the left atrium. Samples for blood gas analyses are drawn from the left atrium (LA) and from a port after the oxygenator where drugs can also be administered. PA, Pulmonary artery; HCU, Heater-cooler unit. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 1222-1228DOI: (10.1016/j.jtcvs.2012.08.011) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Picture of a setup of the lung in the Vivoline ex vivo lung perfusion circuit. Cannula to pulmonary artery in top. Cannula to trachea in bottom. Shunt closed with plastic clamp in upper right corner. White temperature probe crossing the lung. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 1222-1228DOI: (10.1016/j.jtcvs.2012.08.011) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 The practical, circulatory, and ventilatory settings of the different phases during ex vivo lung perfusion. FiO2, Fraction of inspired oxygen. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 1222-1228DOI: (10.1016/j.jtcvs.2012.08.011) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 PVR over time in 6 lungs during ex vivo lung perfusion. PVR, Pulmonary vascular resistance. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 1222-1228DOI: (10.1016/j.jtcvs.2012.08.011) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions