Approach to the Treatment of Methanol Intoxication Jeffrey A. Kraut, MD  American Journal of Kidney Diseases  Volume 68, Issue 1, Pages 161-167 (July 2016) DOI: 10.1053/j.ajkd.2016.02.058 Copyright © 2016 Terms and Conditions

Figure 1 Metabolism of methanol. Methanol undergoes serial oxidation: methanol is catalyzed by the enzyme alcohol dehydrogenase to formaldehyde and then formaldehyde is catalyzed by the enzyme formaldehyde dehydrogenase to formic acid. Folinic acid given to a patient will accelerate the conversion to carbon dioxide (CO2) and water (H2O). Adapted from Rastogi et al11 with permission of the National Kidney Foundation. American Journal of Kidney Diseases 2016 68, 161-167DOI: (10.1053/j.ajkd.2016.02.058) Copyright © 2016 Terms and Conditions