Prognostic Factors and Analysis of Microsatellite Instability in Resected Pulmonary Metastases From Colorectal Carcinoma Giulio Melloni, MD, Claudio.

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Presentation transcript:

Prognostic Factors and Analysis of Microsatellite Instability in Resected Pulmonary Metastases From Colorectal Carcinoma Giulio Melloni, MD, Claudio Doglioni, MD, Alessandro Bandiera, MD, Angelo Carretta, MD, Paola Ciriaco, MD, Gianluigi Arrigoni, MD, Piero Zannini, MD The Annals of Thoracic Surgery Volume 81, Issue 6, Pages 2008-2013 (June 2006) DOI: 10.1016/j.athoracsur.2006.01.007 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier overall survival curve after resection of pulmonary metastases from colorectal carcinoma. Overall 3-, 5-, and 10-year survival rates were 50%, 42%, and 30%, respectively. The Annals of Thoracic Surgery 2006 81, 2008-2013DOI: (10.1016/j.athoracsur.2006.01.007) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier survival curves after resection of pulmonary metastases from colorectal carcinoma. The 5-year survival was 63% in patients with a T1/T2 primary colorectal carcinoma and 34% in patients with a T3/T4 primary colorectal carcinoma. The Annals of Thoracic Surgery 2006 81, 2008-2013DOI: (10.1016/j.athoracsur.2006.01.007) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier survival curves after resection of pulmonary metastases from colorectal carcinoma. The 5-year survival was 44% in patients with complete resection and 0% in patients with incomplete resection. The Annals of Thoracic Surgery 2006 81, 2008-2013DOI: (10.1016/j.athoracsur.2006.01.007) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan-Meier survival curves after resection of pulmonary metastases from colorectal carcinoma in patients grouped according to the International Registry of Lung Metastases (IRLM) classification (group 1, resectable, disease-free interval [DFI] ≥ 36 months and single metastasis; group 2, resectable, DFI < 36 months or multiple metastases; group 3, resectable, DFI < 36 months and multiple metastases; group 4, unresectable). The 5-year survival rates for IRLM 1, IRLM 2, IRLM 3, and IRLM 4 patients were 45%, 47%, 32%, and 0%, respectively. The Annals of Thoracic Surgery 2006 81, 2008-2013DOI: (10.1016/j.athoracsur.2006.01.007) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions