Lung Large Cell Carcinoma Producing Granulocyte-Colony-Stimulating Factor Sachiko Hasegawa, MD, Takashi Suda, MD, Koji Negi, MD, Yoshinobu Hattori, MD

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Presentation transcript:

Lung Large Cell Carcinoma Producing Granulocyte-Colony-Stimulating Factor Sachiko Hasegawa, MD, Takashi Suda, MD, Koji Negi, MD, Yoshinobu Hattori, MD The Annals of Thoracic Surgery Volume 83, Issue 1, Pages 308-310 (January 2007) DOI: 10.1016/j.athoracsur.2006.04.049 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Chest computed tomographic scan taken on admission. A heterogeneous mass of 50 mm × 75 mm in size can be observed in the apicoposterior segment of the left lung (S1+2), adjacent to the pleura. Infiltration in the ribs was suspected. No enlargement of the lymph nodes was found. The Annals of Thoracic Surgery 2007 83, 308-310DOI: (10.1016/j.athoracsur.2006.04.049) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Immunostaining of tumor tissue for granulocyte-colony-stimulating factor (G-CSF). The tumor tissue stained strongly positive for G-CSF, with stained granular bodies predominantly in the cytoplasm. The Annals of Thoracic Surgery 2007 83, 308-310DOI: (10.1016/j.athoracsur.2006.04.049) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Perioperative changes in white blood cell (WBC) count and C-reactive protein (CRP) values. The WBC and CRP values decreased rapidly after operation and returned to normal on hospital day 21. The Annals of Thoracic Surgery 2007 83, 308-310DOI: (10.1016/j.athoracsur.2006.04.049) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions