SDC 2 - Figure S1.

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SDC 2 - Figure S1

SDC 2 - Figure S1. Changes in donor-specific IgG alloantibody levels in the peripheral blood of untreated recipients and those receiving FR70, IgG1 or IgG2a antibody treatment over time. Donor splenic target cells and FITC-labelled goat anti-mouse IgG antibody was used to detect recipient IgG alloantibodies. Change in the levels of peripheral blood IgG alloantibody represented by the median fluorescent intensity (MFI) with time in all treatment groups are shown in the figures where the MFI at day 0 indicates pre-transplant levels of donor-specific antibody. Each line represents alloantibody detected in peripheral blood obtained via tail bleeds from each individual mouse. The mean for the group at each time point is represented by a bar (red). All untreated mice rejected before day 15 and IgG1 treated mice rejected before day 20 therefore alloantibodies could not be analysed at these time points for the corresponding group.