Warfarin Cessation Before Cardiopulmonary Bypass: Lessons Learned from a Randomized Controlled Trial of Oral Vitamin K Richard P. Whitlock, MD, Mark.

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Presentation transcript:

Warfarin Cessation Before Cardiopulmonary Bypass: Lessons Learned from a Randomized Controlled Trial of Oral Vitamin K Richard P. Whitlock, MD, Mark A. Crowther, MD, Theodore E. Warkentin, MD, Mary-Helen Blackall, RN, Forough Farrokhyar, PhD, Kevin H.T. Teoh, MD The Annals of Thoracic Surgery Volume 84, Issue 1, Pages 103-108 (July 2007) DOI: 10.1016/j.athoracsur.2007.03.014 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Mean predicted value for factor V (FV) by occasion of measure. Predicted functional level of coagulation factor V from multilevel model; significant predictor variables include “point,” “time between measures,” and their interaction. Error bars show 95% confidence intervals of mean; dots connected with lines show means. (B4 = just before initiation of cardiopulmonary bypass; ICU = intensive care unit; Postop 5 = postoperative day 5.) The Annals of Thoracic Surgery 2007 84, 103-108DOI: (10.1016/j.athoracsur.2007.03.014) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Mean predicted value for factor II (FII) by occasion of measure. Predicted functional level of coagulation factor II from multilevel model; significant predictor variable is “point” alone. Error bars show 95% confidence intervals of mean; dots connected with lines show means. (B4 = just before initiation of cardiopulmonary bypass; ICU = intensive care unit.) The Annals of Thoracic Surgery 2007 84, 103-108DOI: (10.1016/j.athoracsur.2007.03.014) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions