Identifying and Treating COPD in Cardiac Patients

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Date of download: 7/8/2016 Copyright © The American College of Cardiology. All rights reserved. From: Modified Serum Profiles of Inflammatory and Vasoconstrictive.

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Identifying and Treating COPD in Cardiac Patients Carlo Nozzoli, MD, Bianca Beghè, MD, PhD, Piera Boschetto, MD, PhD, Leonardo M. Fabbri, MD, FCCP CHEST Volume 144, Issue 3, Pages 723-726 (September 2013) DOI: 10.1378/chest.13-0915 Copyright © 2013 The American College of Chest Physicians Terms and Conditions

Figure 1 Aging is characterized by a chronic, low-grade inflammatory status, the so-called “inflamm-aging” that is believed to represent the underlying biologic mechanism responsible for physical function decline in the elderly and the simultaneous development of concomitant chronic diseases, particularly atherosclerosis, coronary artery disease, and COPD. Concomitant chronic diseases are often unrecognized and should be actively searched and treated. ICAM = intercellular adhesion molecule; IFN = interferon; IGF = insulin-like growth factor; IL = interleukin; IL-1Ra = interleukin 1 receptor antagonist; LTA = leukotriene A; MCP = monocyte chemoattractant protein; RANTES = regulated on activation, normal T cell expressed and secreted; TNF = tumor necrosis factor. (Reprinted with permission from De Martinis et al.25) CHEST 2013 144, 723-726DOI: (10.1378/chest.13-0915) Copyright © 2013 The American College of Chest Physicians Terms and Conditions