Case 1: Introduction. Adjuvant Therapy: Should It Be Considered in Older Patients With NSCLC?

Slides:



Advertisements
Similar presentations
Cedars Sinai Medical Center
Advertisements

Advances and Emerging Therapy for Lung Cancer
James R. Rigas Comprehensive Thoracic Oncology Program
Treatment in Advanced Non-Small Cell Lung Cancer.
CHEMOTHERAPY AND BLADDER CANCER Walter Stadler, MD, FACP University of Chicago.
Prof Ramesh S Bilimagga President AROI Group Medical Director - HCG.
Prevention of Early Menopause Study (POEMS)-S0230 Phase III trial of LHRH analog during chemotherapy to reduce ovarian failure in early stage, hormone.
Experience and Outcomes with Hypofractionated Concurrent Chemoradiation for Stage III NSCLC at NCCC Gregory Webb Medical Student.
1 Non–Small-Cell Lung Cancer Diagnosis and Staging EvaluationPurpose Physical examinationIdentify signs Chest x-rayDetermine position, size, number of.
S L I D E 0 Invasive Mediastinal Staging Does Not Improve Outcomes Over PET Alone in Early-Stage NSCLC Treated with SBRT Christopher D. Corso MD PhD, Shane.
2014 Cancer Program Performance Outcomes. Introduction Saint Agnes Medical Center has proudly maintained a American College of Surgeons’ Commission on.
Metastatic Spinal Cord Compression from Non-Small-Cell Lung Cancer Treated with Surgery and Adjuvant Therapies by Yu Tang, Jintao Qu, Juan Wu, Song Li,
Dr Purvish M Parikh MD, DNB, FICP, PhD, ECMO, CPI, MBA 12 th July 2014, Kolkata 17th ICRO PG Teaching Course.
NSCLC stage IIIA type of chemotherapy ? Swiss tumor board Bern – Dr. Christian Monnerat Département Pluridisciplaire d’Oncologie – Hôpital Neuchâtelois.
Neoadjuvant FOLFOX with Bevacizumab but without Pelvic Radiation for Locally Advanced Rectal Cancer Schrag D et al. Proc ASCO 2010;Abstract 3511.
Joan Schiller, MD Professor of Medicine Chief, Division of Hematology/Oncology University of Texas Southwestern Medical Center Deputy Director Simmons.
Adjuvant and Neoadjuvant Therapy in Non- Small Cell Lung Cancer Seminars in Oncology 2oo5;32 (suppl 2):S9-S15 Kyung Hee Medical Center Department of Thoracic.
Complete pathologic responses in the primary of rectal or colon cancer treated with FOLFOX without radiation A. Cercek, M. R. Weiser, K. A. Goodman, D.
Adjuvant Chemotherapy for Non–Small-Cell Lung Cancer in the Elderly: A Population-Based Study in Ontario, Canada JOURNAL OF CLINICAL ONCOLOGY, VOLUME 30.
Neoadjuvant chemotherapy in the treatment of NSCLC Department of Thoracic Oncology, University Hospital Ghent, Belgium Current Opinion in Oncology 2007,
Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal- cell carcinoma after radical nephrectomy: phase III,
Phase III Clinical Trial of FOLFOX with or without Cetuximab in Resected Stage 3 Colon Cancer: Cooperative Group Trial N0147 (NCCTG*,
Outcomes for Elderly, Advanced-Stage Non–Small-Cell Lung Cancer Patients Treated With Bevacizumab in Combination With Carboplatin and Paclitaxel: Analysis.
Volume 18, Issue 6, Pages (September 2015)
Treatment of Stage I and II Non-small Cell Lung Cancer
Perioperative Complications after Neoadjuvant Chemoradiation for Locally-Advanced Esophageal Cancer: A Comparison of Platinum/5-FU and Carboplatin/Paclitaxel.
Belani CP et al. ASCO 2009; Abstract CRA8000. (Oral Presentation)
CHEMO-IMMUNO-TARGET THERAPIES
Schema of the NSABP B-34 trial evaluating adjuvant oral clodronate in patients with resected stage I and II operable breast cancer (Chemo, adjuvant chemotherapy;
Stage I Non Small Cell Lung Cancer (NSCLC): single centre comparison of outcome by treatment with surgery, conventional radiotherapy and stereotactic ablative.
Treatment With Continuous, Hyperfractionated, Accelerated Radiotherapy (CHART) For Non-Small Cell Lung Cancer (NSCLC): The Weston Park Hospital Experience.
The Nurse View: Management of Pancreatic Cancer
Prognosis of younger patients in non-small cell lung cancer
Jabbour E et al. Proc ASH 2015;Abstract 83.
Adjuvant chemotherapy in NSCLC
Table 1 Baseline patient characteristics
Intervista a Angelo Delmonte
Patient Case 1 Patient Case 1: PET/CT Scan.
Figure 2 Underreporting by physicians of specific treatment-associated symptoms by physicians in the TORCH trial Figure 2 | Underreporting by physicians.
Treatment Algorithms in Melanoma: Past, Present, and Future
Highlights From the Inaugural COPD7USA Conference: Focus on Treatment Challenges in COPD.
The Nurse View: Best Practices in Advanced Non-Small Cell Lung Cancer
Introduction. For Pulmonologists by Pulmonologists: Diagnosis of NSCLC in an Age of Biomarkers.
Program Goals. The Role of Chemotherapy in Improving Quality of Life in Advanced NSCLC.
Treatment of Stage I and II Non-small Cell Lung Cancer
Figure 1 Underreporting of treatment-related toxicities by physicians, relative to patients with either advanced-stage lung cancer, or early-stage breast.
Reviewer: Dr. Sunil Verma Date posted: December 12th, 2011
Program Goals. Single vs Dual HER2 Blockade for Metastatic HER2-Positive Breast Cancer.
EVALUTE THE EFFICACY OF ADJUVANT REGIMEN 3FEC- 3T IN STAGE II BREAST CANCER Hai Phong, 2017 LÊ THU HÀ, Ph.D. Nguyễn Khánh Hà, Dr.
MJ O’Connell for the ACCENT Collaborative Group
Brian N. Arnold, MD, Daniel C. Thomas, MD, MPH, Joshua E
Overall survival in the IFCT trial comparing a single agent therapy arm (vinorelbine or gemcitabine) and the doublet carboplatin plus weekly paclitaxel.
Background: Gene Expression
Patient-Centered Management in Advanced Non-Small Cell Lung Cancer
Practical Guidance on the Management of Pan-Negative NSCLC
Treatment of Stage I and II Non-small Cell Lung Cancer
What’s new in stage III lung cancer?
Challenges in LA SCCHN.
The 10-year cumulative incidence of CRC death or death due to other causes in patients treated with adjuvant chemotherapy after surgery for stages II–III.
Elizabeth A. David, MD, MAS, Stina W. Andersen, PhD, Laurel A
Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer. A meta-analysis of two randomized trials E Mitry, A Fields,
RTOG 9704: A Phase III Study of Adjuvant Pre and Post Chemoradiation 5-FU vs. Gemcitabine for Resected Pancreatic Adenocarcinoma A U.S. GI INTERGROUP.
Adjuvant Chemotherapy for Non-small Cell Lung Cancer: Practice Patterns and Outcomes in the General Population of Ontario, Canada  Christopher M. Booth,
Maximizing Disease-Free Survival in Early-Stage HER2-Positive Breast Cancer.
Using Q-learning Method in Identify Optimal Treatment Regime
Treatment of Stage III Non-small Cell Lung Cancer
Machine learning analysis for predicting survival in stage III non-small cell lung cancer patients receiving definitive chemotherapy and proton radiation.
Domenico Galetta, MD, PhD, Lorenzo Spaggiari, MD, PhD 
Early Surgical Results After Pneumonectomy for Non-Small Cell Lung Cancer are not Affected by Preoperative Radiotherapy and Chemotherapy  Tomas Gudbjartsson,
Treating Locally Advanced Disease: An Analysis of Very Large, Hilar Lymph Node Positive Non-Small Cell Lung Cancer Using the National Cancer Data Base 
Presentation transcript:

Adjuvant Therapy: Should It Be Considered in Older Patients With NSCLC?

Case 1: Introduction

Case 1: Imaging and Laboratory Results

Case 1: Imaging and Laboratory Results

Organ Function and Age

Decline in Lung Function With Age and Smoking

Surgical Management and Outcomes in Older Patients with Early-Stage NSCLC

Improved Outcomes With Higher Surgery Rates for Older Patients With NSCLC

Case 1: Surgical Evaluation

Case 1: Surgical Evaluation

CALGB 9633

JBR.10 Trial: Overall Survival

Survival by Age: Meta-Analysis

Overall Survival by Age Group in the Postadoption Cohort 2004-2006*

Postoperative Adjuvant Chemotherapy in Older Patients

Adjuvant Therapy: Cisplatin vs Carboplatin

Case 1: Treatment

Case 2: Patient Introduction

Case 2: Patient Introduction

TREAT Study Design

TREAT Study Results

Interim Analysis of ECOG 1505: Chemotherapy Administered

Interim Analysis of ECOG 1505: Toxicity

Case 2: Treatment

Thank you for participating in this activity.