Per Steinar Halvorsen, MD, Espen W

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Presentation transcript:

Automatic real-time detection of myocardial ischemia by epicardial accelerometer Per Steinar Halvorsen, MD, Espen W. Remme, MSc, PhD, Andreas Espinoza, MD, Helge Skulstad, MD, PhD, Runar Lundblad, MD, PhD, Jacob Bergsland, MD, Lars Hoff, MSc, PhD, Kristin Imenes, MSc, PhD, Thor Edvardsen, MD, PhD, Ole Jakob Elle, MD, PhD, Erik Fosse, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 139, Issue 4, Pages 1026-1032 (April 2010) DOI: 10.1016/j.jtcvs.2009.05.031 Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Anterior view of pig heart showing placement of 3-axis accelerometer in left anterior descending coronary artery perfusion area. Arrow indicates measured circumferential systolic motion. The Journal of Thoracic and Cardiovascular Surgery 2010 139, 1026-1032DOI: (10.1016/j.jtcvs.2009.05.031) Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Experimental study. Accelerometer circumferential velocity and displacement curves are shown with electrocardiography (ECG) at baseline and during left anterior descending coronary artery occlusion (Ischemia). Thick lines indicate automated 150-millisecond measurement interval after peak R on in which peak systolic velocity and displacement are assessed. In this interval, marked decreases in peak velocity and displacement are seen during occlusion, whereas ST segment is almost unchanged. The Journal of Thoracic and Cardiovascular Surgery 2010 139, 1026-1032DOI: (10.1016/j.jtcvs.2009.05.031) Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Experimental study. Left ventricular (LV) pressure-accelerometer displacement loops are shown at baseline, with esmolol infusion, and with left anterior descending coronary artery occlusion (Ischemia). Loop area is decreased during esmolol infusion and further reduced during ischemia. Thick lines indicate systolic contraction in 150-millisecond interval from peak R on electrocardiography; arrows indicate loop direction. The Journal of Thoracic and Cardiovascular Surgery 2010 139, 1026-1032DOI: (10.1016/j.jtcvs.2009.05.031) Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Experimental study. Measurements by accelerometer automated methods at baseline, esmolol infusion, and left anterior descending coronary artery occlusion (Ischemia). Greatest effect during ischemia can be seen in accelerometer-measured midsystolic displacement. Values are mean ± SD. Asterisk indicates P < .05 from baseline; double asterisk indicates P < .01 from baseline; dagger indicates P < .01 from esmolol. The Journal of Thoracic and Cardiovascular Surgery 2010 139, 1026-1032DOI: (10.1016/j.jtcvs.2009.05.031) Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions