Jean-Claude Davin, Ineke J. Ten Berge, Jan J. Weening

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What is the difference between IgA nephropathy and Henoch-Schönlein purpura nephritis? Jean-Claude Davin, Ineke J. Ten Berge, Jan J. Weening Kidney International Volume 59, Issue 3, Pages 823-834 (March 2001) DOI: 10.1046/j.1523-1755.2001.059003823.x Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 1 Relationship between initial clinical signs and risk of chronic renal failure in Henoch-Schönlein purpura nephritis (HSPN)25. Kidney International 2001 59, 823-834DOI: (10.1046/j.1523-1755.2001.059003823.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 2 Immunofluorescence micrograph of a glomerulus from a patient with IgA nephropathy (IgAN) stained for the presence of IgA. A coarsely granular, mesangial staining pattern can be observed (×250). Kidney International 2001 59, 823-834DOI: (10.1046/j.1523-1755.2001.059003823.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 3 Immunofluorescence micrograph of a glomerulus from a patient with HSP nephropathy stained for the presence of IgA. A granular, partial capillary, partial mesangial staining pattern can be observed (×200). Kidney International 2001 59, 823-834DOI: (10.1046/j.1523-1755.2001.059003823.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 4 Light micrograph of a glomerulus from the same patient with IgAN as in Figure 2 showing mesangial expansion caused by accumulation of extracellular matrix and hypercellularity. Methenamine silver (×250). Kidney International 2001 59, 823-834DOI: (10.1046/j.1523-1755.2001.059003823.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 5 Light micrograph of a glomerulus from the same patient with HSP nephropathy as in Figure 3 with influx of neutrophils, fibrinoid necrosis, and intracapillary and extracapillary proliferation, a pattern typical for systemic vasculitis. Methenamine silver (×200). Kidney International 2001 59, 823-834DOI: (10.1046/j.1523-1755.2001.059003823.x) Copyright © 2001 International Society of Nephrology Terms and Conditions