Malaria vaccines and the new malaria agenda B.M. Greenwood, G.A.T. Targett  Clinical Microbiology and Infection  Volume 17, Issue 11, Pages 1600-1607 (November 2011) DOI: 10.1111/j.1469-0691.2011.03612.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Malaria life cycle showing (1) preerythrocytic sporozoite inoculation and invasion of the liver, (2) asexual blood stages, and (3) the sexual cycle and sporogony in the mosquito. Vaccines are being developed against each of these phases of the life cycle. Adapted from Ref. [55] and reprinted with permission. Clinical Microbiology and Infection 2011 17, 1600-1607DOI: (10.1111/j.1469-0691.2011.03612.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Kaplan–Meier curves showing the cumulative proportion of clinical Plasmodium falciparum cases after vaccination of children with RTS,S/ASOIE as compared with controls given rabies vaccine in (a) Korogwe, Tanzania and (b) Kilifi, Kenya [18]. Clinical Microbiology and Infection 2011 17, 1600-1607DOI: (10.1111/j.1469-0691.2011.03612.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions