Polymorphisms of Nucleotide Excision Repair Genes Predict Melanoma Survival  Chunying Li, Ming Yin, Li-E Wang, Christopher I. Amos, Dakai Zhu, Jeffrey E. Lee, Jeffrey E. Gershenwald, Elizabeth A. Grimm, Qingyi Wei  Journal of Investigative Dermatology  Volume 133, Issue 7, Pages 1813-1821 (July 2013) DOI: 10.1038/jid.2012.498 Copyright © 2013 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Kaplan–Meier overall survival analysis for patients with primary melanoma by combined nucleotide excision repair (NER) genotypes (i.e., rs28720291 GG, rs4150314 GG, rs2470458 AG+GG, and rs50871 AC+CC). (a) By 0, 1, 2, and 3 NER variant genotypes (P<0.0001); and (b) by 0–1 and 2–3 NER variant genotypes (P=0.0001). Journal of Investigative Dermatology 2013 133, 1813-1821DOI: (10.1038/jid.2012.498) Copyright © 2013 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Kaplan–Meier overall survival curves for patients with primary melanoma of 0–1 and 2–3 nucleotide excision repair (NER) variant genotypes (i.e., rs28720291 GG, rs4150314 GG, rs2470458 AG+GG, and rs50871 AC+CC) by tumor-related characters. (a, b) By tumor Breslow thickness (P<0.0001); (c, d) by sentinel lymph node biopsy (SLNB) (P<0.0001); (e, f) by mitotic rate (P<0.0001); (g, h) by American Joint Committee on Cancer stages (P<0.0001); (i, j) by ulceration (P<0.0001); and (k, l) by primary tumor anatomic site (P<0.0001). Journal of Investigative Dermatology 2013 133, 1813-1821DOI: (10.1038/jid.2012.498) Copyright © 2013 The Society for Investigative Dermatology, Inc Terms and Conditions