A Feasibility and Safety Study of Bronchoscopic Thermal Vapor Ablation: A Novel Emphysema Therapy Gregory I. Snell, MD, Peter Hopkins, MBBS, Glen Westall,

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Presentation transcript:

A Feasibility and Safety Study of Bronchoscopic Thermal Vapor Ablation: A Novel Emphysema Therapy Gregory I. Snell, MD, Peter Hopkins, MBBS, Glen Westall, PhD, Lynda Holsworth, BNurs, Anne Carle, RN, Trevor J. Williams, MD The Annals of Thoracic Surgery Volume 88, Issue 6, Pages 1993-1998 (December 2009) DOI: 10.1016/j.athoracsur.2009.06.038 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Uptake Medical bronchial thermal vapor ablation generator and catheter (Uptake Medical Corporation, Seattle, WA). The Annals of Thoracic Surgery 2009 88, 1993-1998DOI: (10.1016/j.athoracsur.2009.06.038) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Individual changes in treated lobar volume, comparing baseline (0 months), 3 months, and 6 months in 11 patients. The Annals of Thoracic Surgery 2009 88, 1993-1998DOI: (10.1016/j.athoracsur.2009.06.038) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Chest computed tomography transverse slice example of left-sided unilateral bronchial thermal vapor ablation demonstrates loss of the target left upper lobe volume at (A) baseline, (B) 3 months, and (C) 6 months. The Annals of Thoracic Surgery 2009 88, 1993-1998DOI: (10.1016/j.athoracsur.2009.06.038) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Individual changes in St. George Respiratory Questionnaire Total Sccores comparing baseline (0 months) and 6 months. The Annals of Thoracic Surgery 2009 88, 1993-1998DOI: (10.1016/j.athoracsur.2009.06.038) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Individual forced expiratory volume in 1 second (FEV1), residual volume (RV), and diffusion capacity of the lung for carbon monoxide (Dlco) results at baseline (0 months) and at 1, 3, and 6 months in 11 patients. The Annals of Thoracic Surgery 2009 88, 1993-1998DOI: (10.1016/j.athoracsur.2009.06.038) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions