Volume 144, Issue 5, Pages (May 2013)

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Volume 144, Issue 5, Pages 1024-1030 (May 2013) Prognostic Gene Expression Signature for Patients With Hepatitis C–Related Early- Stage Cirrhosis Yujin Hoshida, Augusto Villanueva, Angelo Sangiovanni, Manel Sole, Chin Hur, Karin L. Andersson, Raymond T. Chung, Joshua Gould, Kensuke Kojima, Supriya Gupta, Bradley Taylor, Andrew Crenshaw, Stacey Gabriel, Beatriz Minguez, Massimo Iavarone, Scott L. Friedman, Massimo Colombo, Josep M. Llovet, Todd R. Golub Gastroenterology Volume 144, Issue 5, Pages 1024-1030 (May 2013) DOI: 10.1053/j.gastro.2013.01.021 Copyright © 2013 AGA Institute Terms and Conditions

Figure 1 Study design. Needle liver biopsy specimens collected from the prospectively followed-up patient cohort were subjected to whole-genome gene expression profiling. Gastroenterology 2013 144, 1024-1030DOI: (10.1053/j.gastro.2013.01.021) Copyright © 2013 AGA Institute Terms and Conditions

Figure 2 Probabilities of survival and development of HCC. Curves are shown for (A) overall death and (B) development of HCC according to the level of expression of the 186-gene signature among all 216 patients. Time 0 indicates the time of enrollment. Gastroenterology 2013 144, 1024-1030DOI: (10.1053/j.gastro.2013.01.021) Copyright © 2013 AGA Institute Terms and Conditions