by Wolfram Springer, Alexander von Ruecker, and Roswitha Dickerhoff

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Presentation transcript:

by Wolfram Springer, Alexander von Ruecker, and Roswitha Dickerhoff Difficulties in Determining Prophylactic Transfusion Thresholds of Platelets in Leukemia Patients by Wolfram Springer, Alexander von Ruecker, and Roswitha Dickerhoff Blood Volume 92(6):2183-2184 September 15, 1998 ©1998 by American Society of Hematology

Flow cytometric analysis (contour plot) of platelets and platelet-derived microparticles in a patient with acute myelogenous leukemia (A) and a normal individual (B) using anti-CD61 and anti-CD42b antibodies. Flow cytometric analysis (contour plot) of platelets and platelet-derived microparticles in a patient with acute myelogenous leukemia (A) and a normal individual (B) using anti-CD61 and anti-CD42b antibodies. Whole blood was treated with platelet-specific fluorescent antibodies as described previously.5CD61+/CD42b+ events (n = 50,000), representing platelets and platelet-derived microparticles, were gated and are shown in forward and side scatter mode. Normal-size platelets (>2 fL) and platelet-derived microparticles (<2 fL) were defined as shown in the graph by a size-threshold of 2 fL, established with the help of fluorescent calibration beads. Wolfram Springer et al. Blood 1998;92:2183-2184 ©1998 by American Society of Hematology