Do CNV Subtypes Matter for Prognosis, Diagnosis, and Treatment?

Slides:



Advertisements
Similar presentations
The Diabetic Retinopathy Clinical Research Network
Advertisements

AMD Trials and Treatments:
The Diabetic Retinopathy Clinical Research Network
The Diabetic Retinopathy Clinical Research Network
EVEREST II Study Design Multicenter Randomized in a 2:1 ratio to either percutaneous or conventional surgery for the repair or replacement of the mitral.
Macugen (pegaptanib sodium injection) Advisory Committee Meeting August 27, 2004 Jennifer D. Harris, MD Medical Officer Division of Anti-Inflammatory,
The Diabetic Retinopathy Clinical Research Network Intravitreal Ranibizumab for Diabetic Macular Edema with Prompt vs Deferred Laser Treatment: 3-year.
A Review of Ranibizumab Clinical Trial Data in Exudative Age-Related Macular Degeneration and How to Translate It into Daily Practice Ophthalmologica 2011;225:112–119.
가톨릭대학교 의과대학 안과 및 시과학 교실 R3 장동진 / Pf.이원기
Upfront Combination Therapy vs Step-Up Approach for PAH:
The Diabetic Retinopathy Clinical Research Network
Finding the Right Fit: Personalizing Treatment in Metastatic Castration-Resistant Prostate Cancer.
Copyright © 2013 American Medical Association. All rights reserved.
New Paradigms for HER2-Positive Early Breast Cancer: Implications and Application.
Endocrine Combinations in HR-Positive MBC: The Future Is Now
Protocol U Short-Term Evaluation of Combination Dexamethasone + Ranibizumab vs. Ranibizumab Alone for Persistent Central-Involved DME Following Anti-VEGF.
nAMD: Choosing the Best Treatment for your Patient
Exploring Early Combination Therapy in PAH
Key Developments From Recent Clinical Trials
Making Decisions With Your Osteoarthritis Patients
5 Things NPs and PAs Need to Know About Tardive Dyskinesia
CDK 4 and 6 Inhibitors in HR-Positive Breast Cancer: A Clinical Update
Progression After Cancer Immunotherapy in Advanced NSCLC
Clinical Trials to Real World:
PAD Patients vs Post-ACS Patients:
A New Era for NOACs:.
The Latest Data on Oral Prostacyclin Therapy in PAH
Updates on Noninvasive Ventilation in COPD
Metastatic Renal Cell Carcinoma
PCP Perspectives Clinical Considerations in Hyperkalemia
Clinical Cases in Glaucoma Treatment
nAMD: Switching Therapies - what you need to know
The Diabetic Retinopathy Clinical Research Network
Tailoring Hemophilia Prophylaxis Therapy
Novel and Emerging Approaches to Treating CLL
Managing gBRCA-Positive Metastatic Breast Cancer
nAMD: New Drugs and Practice Patterns to Improve Patient Outcomes
Multidisciplinary Perspectives on Interstitial Lung Diseases
Selected Highlights of the Latest Advances in PAH
Updates on Anti-VEGF Therapy: Improving Durability and Predicting Response.
A Hard Look at Cardiogenic Shock: IABP-SHOCK II Revisited
Immunotherapy for cSCC
Observational Studies vs. Randomized Controlled Trials (RCT)
Translating the Latest and Greatest Advances in PAH Into Clinical Practice.
EARLY Combination Therapy in PAH: What Every Cardiologist Needs to Know.
JAMA Ophthalmology Journal Club Slides: Ranibizumab with or without verteporfin photodynamic therapy for polypoidal choroidal vasculopathy Koh A, Lai TYY,
Key Questions for nAMD Treatment Success
Intro: Biomarkers in RA
Wet AMD trials Hibba Soomro.
Short-Term Evaluation of Combination
Trials and Tribulations in VTE: How Do Real-World Data Fit In?
nAMD: Choosing the Best Treatment for your Patient
Addressing Pneumococcal Disease in Latino Communities
Defining Patient-Centered Care: Spotlight on Advanced Non-Small Cell Lung Cancer.
What's New in PAH?.
Are We Making Progress in the Management of Huntington Disease?
Practical Guidance on the Management of Pan-Negative NSCLC
Should We Dry the Retina Faster for Longer
Emerging Regimens in Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Applying the Latest Data on Treat-and-Extend Strategies to Clinical Cases in nAMD.
Secondary Progressive Multiple Sclerosis: What Do We Know and Where Are We Heading?
Addressing Cardiovascular Events:
Real-World Evidence.
Early Treatment of Diabetic Retinopathy
Enthesitis in Psoriatic Arthritis: Disease, Diagnosis and Decisions
BRIDGING CVD AND T2DM: LESSONS LEARNED FROM OUTCOME TRIALS
Changing Paradigms in Relapsed/Refractory Indolent NHL
nAMD: Why Anatomical Outcomes Matter
What's New in NOACs in AF?.
Translating Data From Trial to Practice
Presentation transcript:

Do CNV Subtypes Matter for Prognosis, Diagnosis, and Treatment?

Program Overview

CNV Subtypes and Clinical Features

Identifying and Diagnosing Different CNV Subtypes

Treatment Options for CNV Subtypes

DRAGON Study Schema: Phase 4, 24-Month, Randomized, Double-Masked, Controlled, Multicenter Study

At Baseline, 41.7% of Patients Were Diagnosed With PCV

Ranibizumab Treatment Resulted in BCVA Improvements, Regardless of PCV Status

Number of Injections Administered Was Similar for Patients With PCV and non-PCV

LUMINOUS Trial: Mean VA Outcomes in Global Population: 1-Year Follow-Up Data

LUMINOUS Trial: Safety Outcomes in Global Population: 1-Year Follow-Up Data

EVEREST II: The Largest Multicenter RCT Conducted for PCV

EVEREST II: Treatment Schedule

BCVA Change From Baseline to Month 12 and Complete Polyp Regression at Month 12

Number of Injections Received in Study Eye Prior to Month 12

Number of vPDT/Sham PDT Received in the Study Eye Prior to Month 12

PLANET Study: Aflibercept Monotherapy vs Aflibercept Plus PDT in Patients With PCV

CATT Study: RAP Subgroup Analysis

Importance of Differentiating RAP Lesions

Concluding Remarks

Abbreviations

Abbreviations (cont)